Shake Flonase Nasal Spray gently before each use.Patients should use Flonase Nasal Spray at regular intervals since its effectiveness depends on its regular use. Discontinue Flonase Nasal Spray if such reactions occur Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. After the first few days, patients may be able to reduce their dose to 1 spray in each nostril once daily for maintenance therapy.Maximum total daily doses should not exceed 2 sprays in each nostril (total dose, 200 mcg/day). Do not stop using Flonase Nasal Spray unless your healthcare provider tells you to do so.Symptoms of nasal septal perforation may include:•crusting in the nose•nose bleeds•runny nose•whistling sound when you breathe•You should not use Flonase Nasal Spray until your nose has healed if you have a sore in your nose, have had surgery on your nose, or if your nose has been injured.•You should have regular eye exams while you use Flonase Nasal Spray.•Call your healthcare provider or get emergency medical care if you get any of the following signs of a serious allergic reaction:•rash•hives•swelling of your face, mouth, and tongue•breathing problems•). The use of strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, ketoconazole, telithromycin, conivaptan, lopinavir, nefazodone, voriconazole) with Flonase Nasal Spray is not recommended because increased systemic corticosteroid adverse effects may occur.A drug interaction trial with fluticasone propionate aqueous nasal spray in healthy subjects has shown that ritonavir (a strong CYP3A4 inhibitor) can significantly increase plasma fluticasone propionate exposure, resulting in significantly reduced serum cortisol concentrations Coadministration of orally inhaled fluticasone propionate (1,000 mcg) and ketoconazole (200 mg once daily) resulted in a 1.9-fold increase in plasma fluticasone propionate exposure and a 45% decrease in plasma cortisol area under the curve (AUC), but had no effect on urinary excretion of cortisol.Hepatic impairment: Monitor patients for signs of increased drug exposure. Please talk to your doctor about your optio ... Allegra (fexofenadine) is an antihistamine and does not have to be separated from antibiotics that you take. Glaucoma and cataracts have been associated with nasal corticosteroid use. It is available to different forms, but the most common are nasal spray and topical creams.There are various fluticasone products available in the market. All rights reserved. SOME people can tolerate repeat of 800mg every 8 hours.Zyrtec (cetirizine) should not have any direct effect on pheochromocytoma.Yes. Drug information provided by: IBM Micromedex It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. During your treatment, you may need to go for a regular eye exam to detect if there are any problems. Redness 5. Since fluticasone propionate is predominantly cleared by hepatic metabolism, impairment of liver function may lead to accumulation of fluticasone propionate in plasma. It may take 2 to 3 days for the medication to reach its full effect. •Press down and releasetimes until a fine spray appears (See Figure C). Select one or more newsletters to continue. Do not use Flonase Nasal Spray for a condition for which it was not prescribed. Usually polyps that cause chronic symptoms are helped by surgery.