Would you like Wikipedia to always look as professional and up-to-date? Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines.The fundamental goal of treatment should be the prevention of the important "endpoints" of In the United States, the JNC7 (The Seventh Report of the Joint National Committee on Prevention of Detection, Evaluation and Treatment of High Blood Pressure) recommends starting with a Despite thiazides being cheap, effective, and recommended as the best first-line drug for hypertension by many experts, they are not prescribed as often as some newer drugs. Thiazide diuretics promote potassium and magnesium excretion but, unlike loop diuretics, inhibit calcium excretion. The thiazide-like diuretics are more effective than the thiazide-type diuretics for reducing the risk of heart attack, stroke, and heart failure in persons with high blood pressure and the thiazide-like and thiazide-type diuretics have similar rates of adverse effects. Thiazide diuretics (water pills) are medications that are used to treat high blood pressure (hypertension) and reduce fluid accumulation in the body. Br J Pharmacol, 2010, 161(1), 1-16 Pubmed ; Europäisches Arzneibuch PhEur; Krakoff L.R. Central alpha agonists lower blood pressure by stimulating alpha-receptors in the brain which open peripheral arteries easing blood flow. Thiazide (/ ˈ θ aɪ ə z aɪ d /) là một loại phân tử và một lớp các thuốc lợi tiểu thường được sử dụng để điều trị tăng huyết áp (huyết áp cao) và phù nề (như rằng do suy tim, suy gan, hoặc suy thận).. Các thuốc lợi tiểu thiazide và thiazide làm giảm nguy cơ tử vong, đột quỵ, đau tim và suy tim do tăng huyết áp. L. Loop diuretics; P. Potassium-sparing diuretics; T. Thiazide diuretics; Media in category "Diuretics" The following 19 files are in this category, out of 19 total. It will teach you all you need to know about diuretics, sodium, potassium and much, much more. Files are available under licenses specified on their description page. Examples include metolazone and chlorthalidone. Some, such as indapamide are considered thiazide-like diuretics, but do not necessarily have the same mechanism. A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but does not have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure.. : CD005185. Thiazide and Thiazide-Like Diuretics Perspectives on Individualization of Drug and Dose Based on Therapeutic Index Matthew R. Weir, Rajiv Agarwal See related article, pp 1104–1109 P eterzan et al1 have provided an important new meta-analysis of the dose-response relationships for 2 different thiazide diuretics and 1 thiazide-like diuretic. Thiazide (/ ˈθaɪəzaɪd /) refers to both a class of sulfur-containing organic molecules and a class of diuretics based on the chemical structure of benzothiadiazine.

Le délai de l'apparition de l'activité diurétique est d'environ 2 heures.

No. Cochrane Database of Systematic Reviews 2011, Issue 10. Art. Such questions include issues of mechanism of action, comparability to loop‐diuretics in their … Examples include metolazone and chlorthalidone.. Central alpha agonists, such as clonidine, are usually prescribed when all other anti-hypertensive medications have failed. 2008. accessed online at Aung K, Htay T. Thiazide diuretics and the risk of hip fracture. The members of this class of diuretics are derived from benzothiadiazine.They control hypertension in part by inhibiting reabsorption of sodium (Na +) and chloride (Cl −) ions from the distal convoluted tubules in the kidneys by blocking the thiazide-sensitive Na +-Cl − symporter. Thiazide diuretics are less potent than loop diuretics and are ineffective when the glomerular filtration rate falls below about 30 ml/min.