An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Available for Android and iOS devices. These medications are not usually taken together. This may cause blood pressure to fall excessively, especially when you rise from a sitting or lying position. tizanidine and xanax. Common medications that may interact with tizanidine include: Alcohol may worsen the side effects of tizanidine such as drowsiness and dizziness.Note that this list is not all-inclusive and includes only common medications that may interact with tizanidine. Do not stop using any medications without first talking to your doctor.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Caffeine may significantly increase the blood levels and effects of tiZANidine in some patients. Using tiZANidine together with ethanol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Alcohol Alcohol increased the AUC of tizanidine by approximately 20%, while also increasing its C max by approximately 15%. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Check with your health care … Consult your healthcare professional (e.g., doctor or … A 24-year-old male asked: What will happen if I mix 8mg of Zanaflex and 4mg of Xanax (alprazolam) as a sleep aid? These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Revision date: November 6, 2019.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You should avoid or limit the use of alcohol during treatment. Both tizanidine and alcohol (beverage) can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing ). You should refer to the prescribing information for tizanidine for a complete list of interactions.Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use tizanidine only for the indication prescribed.Copyright 1996-2020 Drugs.com. We comply with the HONcode standard for trustworthy health information - You should avoid or limit the use of alcohol during treatment. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Speak to your doctor about how drug interactions should be managed. Because of this short duration of effect, tizanidine may be dosed on an "as needed" basis during times when muscle spasms are at their most severe.Medicines that interact with tizanidine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with tizanidine. In addition, these medications may also have additive effects in … The risk of other side effects such as drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm may also increase. Dangerous sedation: the mixture of a muscle relaxer ( Zanaflex) and a tranquilizer ( benzodiazepine ) especially a 4 mg dose can lead to severe sedation and loss of consc ... Read … In addition, these medications may also have additive effects in lowering your blood pressure. Muscle Relaxants for Back Pain Are Soaring: Are They Safe? If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Select one or more newsletters to continue. Does Tizanidine HCL Interact with other Medications? It is important to tell your doctor about all other medications you use, including vitamins and herbs. This was associated with an increase in side effects of tizanidine. Select one or more newsletters to continue. Seniors may be more susceptible to the side effects of tizanidine. Severe Interactions. Both tizanidine and alcohol (beverage) can increase the risk of hypotension. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. 46 years experience Family Medicine. This can cause increased side effects from tizanidine. Zanaflex (tizanidine) is a skeletal muscle relaxant used to treat and manage muscle spasms and tightness due to multiple sclerosis or spinal cord injury. Muscle Relaxants for Back Pain Are Soaring: Are They Safe? Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. Do not stop using any medications without first talking to your doctor.Using tiZANidine together with ethanol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Talk to your doctor if you have any questions or concerns. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. May interact with a number of other drugs including those metabolized by hepatic enzymes CYP1A2 (such as fluvoxamine, ciprofloxacin, some antiarrhythmics), and oral contraceptives. Tizanidine has mild interactions with at least 84 different drugs. This information does not contain all possible interactions or adverse effects.