Although bleeding can occur in the target range, the risk increases with a rising INR. user's use of or reliance upon this material. Also make sure there is a valid indication for starting warfarin. When adjusting maintenance doses for high or low INR values, it is important to think in terms of adjusting the dose as a percentage-based change.

Warfarin is usually started with loading doses. (Starting dose should be based on patient age; presence of  interacting A systematic review included three studies, but none showed improvements in the proportion of patients within the target range.An Australian trial of point-of-care testing in general practice included INR testing as well as other tests.

Diet, age and dose also influence the anticoagulant effect.


Regular monitoring and good patient education are important for successful treatment.Pharmacy Department, Flinders Medical Centre, AdelaideIntegrated Cardiovascular Clinical Network, Country Health South AustraliaPharmacy Department, Flinders Medical Centre, AdelaideReasonable care is taken to provide accurate information at the time of creation. Review the contraindications to therapy and the clinical conditions that may increase risks associated with warfarin therapy. Pediatric dosage explained.

Patients use algorithms to determine any necessary dose adjustments following INR measurement.A number of randomised controlled trials of both self-monitoring and self-management have been included in systematic reviews and meta-analyses.Few studies have compared INR point-of-care testing by GPs with laboratory testing.