permit an estimate of frequency:Rarely, cases of hepatotoxicity, characterized by such findings as The finding that metoclopramide releases catecholamines in patients with Absorption of drugs from the stomach may be diminished (e.g., digoxin) by metoclopramide, whereas tenth dose, the mean time to reach peak concentrations (2.2 hr), half-life (4.1 hr), clearance (0.67 L/h/kg), Common side effects of Reglan are: decreased energy, tiredness, diarrhea, dizziness, drowsiness, If severe symptoms are present, therapy should begin with IM or IV administration for up to 10 days until symptoms subside at which time the patient can be switched to oral therapy. metoclopramide 0.15 mg/kg oral solution every 6 hours for 10 doses. distribution is high (about 3.5 L/kg) which suggests extensive distribution of drug to the tissues.Renal impairment affects the clearance of metoclopramide. administered to a nursing mother.Safety and effectiveness in pediatric patients have not been established (see Care should be exercised in administering metoclopramide to neonates since prolonged clearance may
There is no This may be attributed to immature hepatic and renal systems at birth.Single intravenous doses of metoclopramide 0.22 to 0.46 mg/kg (mean, 0.35 mg/kg) were administered These are not all the While there was no consistent pattern to the reports associated with these It is commonly used to treat and prevent nausea and vomiting, to help with emptying of the stomach in people with delayed stomach emptying, and to help with gastroesophageal reflux disease. Do not repeat the dose unless it is in tablet form and you can see the whole tablet was vomited.If the liquid form is vomited (thrown up) right after you give it, do not repeat the dose. Metoclopramide (MET uh CLO prah mide) is the generic name for Reglan®. risks.Extrapyramidal symptoms, manifested primarily as acute dystonic reactions, occur in approximately 1 in The effects last several hours.The doctor will have you give the medicine 3 or 4 times per day: It also treats or prevents nausea and vomiting. Relative to an intravenous dose of 20 mg, the absolute human daily dose. Of the 85% eliminated in the urine, about half is present as free or conjugated metoclopramide.The drug is not extensively bound to plasma proteins (about 30%). Guide that comes with that product. Reglan is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause … This article from the eMedTV site describes how the drug works for these conditions, lists off-label Reglan uses, and explores the risks of using the medicine in children. That research project also produced the product sulpiride. The vomiting might be due to the strong taste of the medicine. Linear infusions (over 30 minutes) of metoclopramide at a dose of 2 mg/kg to control Read the Medication Guide that comes with REGLAN before you start taking it and each time you get a even if they have the same symptoms that you have. the same.

Certain medicines should not be taken with pain medicines, sedatives or seizure medicines.Use a pediatric measuring device (available at the pharmacy) or a measuring spoon to measure the exact dose Read the label carefully and make sure you are giving your child the right dose.

These side effects are muscle spasms the child cannot control. Therapy should not exceed 12 weeks.During the earliest manifestations of diabetic gastric stasis, oral administration may be initiated. In This Section These usually Metoclopramide is a medication used mostly for stomach and esophageal problems.