More frequently reported side effects include: constipation, headache, and hypertension. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). COVID-19 is an emerging, rapidly evolving situation. This is true even if they take medications such as memantine to help treat it.Keep these considerations in mind if your doctor prescribes memantine for you.A prescription for this medication is refillable. Symptoms may include:If you develop these symptoms, call 911 or go to the nearest emergency room.Tell your doctor if you’re pregnant or plan to become pregnant. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.

Sharing this information can help you avoid potential interactions.If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.Taking these drugs with memantine can increase the amount of memantine in your body. As her MMSE was 12/30, she was prescribed a combination treatment with memantine. 2019 Feb 28;19(1):33. doi: 10.1186/s12883-019-1260-3. Do not mix oral solution with any other liquid. Serious side effects and their symptoms can include the following:Memantine oral tablet can interact with several other medications. Method. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Other side effects not listed may also occur in some patients. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. 2008 Mar;69(3):339-40. doi: 10.4088/jcp.v69n0301.Herrmann N, Gauthier S, Boneva N, Lemming OM; 10158 Investigators.Int Psychogeriatr. It comes with serious risks if you don’t take it as prescribed.If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their All people with Alzheimer’s disease have worsening symptoms over time. Agitation, one of the most distressing NPS, lacks well-established long-term interventions that are both effective and safe. Consequently, there is a large pool of high-quality evidence that supports memantine’s use in moderate-to-severe cases of Alzheimer’s disease (AD) . Common side effects … Epub 2017 Jan 11.Front Pharmacol. Your doctor will write the number of refills authorized on your prescription.During your treatment with this drug, your doctor will monitor your cognitive function (how well your memory and thought processes function). 31 participants with partial or nonresponse to their current antidepressant were randomized (from 2006–2011) to add memantine (flexible dose 5–20 mg/day, with all memantine group participants reaching the dose of 20 mg/day) (n= 15) or placebo (n= 16) to their existing treatment for 8 weeks. Currently there are relatively few studies of antidepressants for the treatment of agitation and psychosis in dementia.The SSRIs sertraline and citalopram were associated with a reduction in symptoms of agitation when compared to placebo in two studies. Our website services, content, and products are for informational purposes only. Select one or more newsletters to continue. Please enable it to take advantage of the complete set of features! When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.Many insurance companies require a prior authorization for this drug. Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Pathologic or excessive receptor activation, as postulated to occur during AD, prevents magnesium from reentering and blocking the channel pore resulting in a chronically open state and excessive calcium influx. 2011 May;25(5):425-33. doi: 10.2165/11588160-000000000-00000.Int J Geriatr Psychiatry. This drug should be used during pregnancy only if the potential benefit justifies the potential risk.Memantine oral tablet is used for long-term treatment. Behavioral and psychological symptoms that could affect patient safety, patient health, and patient care may not be fully treated with nonpharmacological interventions alone. Also tell them about any vitamins, herbs, and supplements you use. For people with moderate to severe Alzheimer’s disease, NYU Langone doctors may prescribe a medication called memantine, or Namenda ®.A brain chemical called glutamate is important for memory and learning, but in large amounts glutamate can kill brain … However, be sure to take the dosage your doctor prescribes for you. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Name must be less than 100 characters They might be restless, unable to sleep, or pace back and forth. Commonly prescribed drugs Hamilton Anxiety Rating Scale (HARS) [Time Frame: baseline & week 8] [Designated as safety issue: No]Each item is scored on a scale of 0 (not present) to 4 (severe), with a total score range of 0-56, where ; 17 indicates mild severity, 18-24 mild to moderate severity and 25-30 moderate to severe. There is some evidence that memantine has a positive effect on mood, behaviour and agitation. 2019 Mar 20;3(3):CD003154. While non-pharmacological interventions are the suggested first-line treatment, it isn't effective in managing symptoms for every patient. 2019 May 22;10:540. doi: 10.3389/fphar.2019.00540. The FDA has officially approved memantine for the treatment of certain cases of Alzheimer’s disease, and this is the most typical medical use of memantine. Epub 2013 Mar 8.CNS Drugs. Unable to load your collection due to an error The following list contains some of the key side effects that may occur while taking memantine. This list does not contain all drugs that may interact with memantine.Before taking memantine, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. A class of drugs is a group of medications that work in a similar way. 2003;(3):CD003154. It helps reduce dementia symptoms, but it doesn’t cure Alzheimer’s. Available for Android and iOS devices. All rights reserved. You should not need a new prescription for this medication to be refilled. Therefore, pharmacological management may become necessary to stem and alleviate symptom progression. Questionable efficacy of memantine to diminish aggression/agitation. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products.