A Blood Disorder 2. Common side effects of Paxil include: headache, nervousness, restlessness, drowsiness, dizziness, nasal irritation, sleep problems (insomnia), nausea, constipation, weight changes, decreased sex drive, impotence, difficulty having an orgasm, dry mouth, yawning, or ; ringing in the ears. What Are Side Effects of Paxil? However, there have been postmarketing reports of patients developing elevated serum transaminases resulting in severe liver dysfunction, as well as, a few cases of elevated liver function tests resulting in death secondary to liver necrosis.Epidemiological studies, primarily in patients aged 50 years or older, have shown an increased risk of bone fractures in patients receiving SSRIs or TCAs.1. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. People typically start on 10 mg/day and increase this by 10 mg per day at intervals of at least 1 week. BMJ 306 (1993): 14323. Jacob S, Spinler SA "Hyponatremia associated with selective serotonin-reuptake inhibitors in older adults." Boyer WF, Blumhardt CL "The safety profile of paroxetine." Am J Med 119 (2006): e1-322. from a population of unknown size, it is not always possible to reliably Paruchuri P, Godkar D, Anandacoomarswamy D, Sheth K, Niranjan S "Rare case of serotonin syndrome with therapeutic doses of paroxetine." Cerner Multum, Inc. "UK Summary of Product Characteristics."   Typically, these side effects will go away within a … decreased sex drive, impotence, abnormal ejaculation, or difficulty having an orgasm. In those cases with a known outcome, patients recovered Because these reactions are reported voluntarily patients treated with PAXIL CR and at a rate greater than in placebo-treated Learn to Spot Depression: Symptoms, Warning Signs, Medication Do not start or stop taking Paxil during pregnancy without your doctor's advice. Paxil may inhibit how well the body breaks down thioridazine and pimozide, which may increase the levels of these two drugs in the blood. Am J Med 120 (2007): 448-5410. Doctors will typically start adults on Depending on the person’s response to Paxil, the doctor may increase the dose by 10 mg every week if needed. Paxil passes into breast milk and may harm a nursing baby. Chua TP, Vong SK "Hyponatraemia associated with paroxetine." O 03. BMJ 305 (1992): 133227. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Studies have shown that infants exposed during the first trimester had a Paxil interacts with monoamine oxidase inhibitors (MAOIs). paresthesia, agitation, confusion, myoclonus, concentration impaired, The most common side effects associated with treatment discontinuation in clinical trials included somnolence, The most common dose-dependent side effects associated with treatment discontinuation in clinical trials for the treatment of The most common side effects associated with treatment discontinuation in the treatment of vasomotor symptoms in clinical trials included In a placebo-controlled study in elderly patients with major depressive disorder, the most common side effects associated with treatment discontinuation of controlled-release paroxetine included nausea, headache, depression, and abnormal LFTs.There may be adaptation to some side effects (such as nausea and dizziness) but not to others (such as dry mouth, somnolence, and asthenia) with continued therapy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. detail in other sections of the prescribing information:Because clinical trials are conducted under widely J Clin Psychopharmacol 15 (1995): 374-512. J Clin Psychiatry 61 (2000): 28-3617. estimates of the incidence and severity of untoward experiences involving taste perversion, UTI, menstrual disorder, urinary frequency, urination because patients and healthcare providers may be reluctant to discuss them. dysfunction in the Studies 1 and 2 (nonelderly patients with MDD), 4, 5, 6, 7,