In three placebo-controlled studies, symptom evaluation and uroflowmetric measurements were performed approximately 24 hours following dosing. Patients should be advised about the possibility of priapism as a result of treatment with Terazosin Capsules and other similar medications.
The incidence of urinary tract infection was significantly lower in the patients receiving terazosin than in patients receiving placebo. Patients should be advised about the possibility of priapism as a result of treatment with Terazosin Capsules and other similar medications. The 2 mg, 5 mg and 10 mg capsules are not indicated as initial therapy.

Double-blind, Placebo-controlled StudiesTerazosin Capsules, like other alpha-adrenergic blocking agents, can cause marked lowering of blood pressure, especially postural hypotension, and syncope in association with the first dose or first few days of therapy. In a long-term, open-label, non-placebo controlled clinical trial, 181 men were followed for 2 years and 58 of these men were followed for 30 months. This typically occurs when you stand after lying down or sitting. Adverse Reactions

Syncope is believed to be due to an excessive postural hypotensive effect, although occasionally the syncopal episode has been preceded by about of severe supraventricular tachycardia with heart rates of 120-160 beats per minute. Discontinuation During Placebo-controlled Trials Benign Prostatic HyperplasiaTable 3.

Terazosin Oral capsule 10mg Drug Medication Dosage information.

The dose may be increased by approximately doubling at weekly or bi-weekly intervals to achieve the desired reduction in symptoms. Terazosin Capsules, USP for oral ingestion are supplied in four dosage strengths containing terazosin hydrochloride equivalent to 1 mg, 2 mg, 5 mg, or 10 mg of terazosin.

If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Children—Use and dose must be determined by your doctor. The safety profile of patients treated in the long-term open-label study was similar to that observed in the controlled studies. Terazosin Capsules are also used to treat benign prostatic hyperplasia (BPH) in men.

Blood pressure responses were measured at the end of the dosing interval (usually 24 hours) and effects were shown to persist throughout the interval, with the usual supine responses 5-10 mmHg systolic and 3.5-8 mmHg diastolic greater than placebo. If you have a prolonged abnormal erection, call your doctor or go to an emergency room as soon as possible.Follow your doctor’s instructions about how to take Terazosin Capsules. Further dose response and dose duration studies are being carried out. Limited measurements of peak response (2-3 hours after dosing) during chronic terazosin administration indicate that it is greater than about twice the trough (24 hour) response, suggesting some attenuation of response at 24 hours, presumably due to a fall in blood terazosin concentrations at the end of the dose interval.

- If you have any further questions, ask your doctor or pharmacist. The risk of the events is greatest during the initial seven days of treatment, but continues at all time intervals. The 1 mg, 2 mg, 5 mg and 10 mg capsules contain the following inactive ingredients: lactose monohydrate, starch, stearic acid and talc.


The plasma levels peak about one hour after dosing, and then decline with a half-life of approximately 12 hours.

They should also be advised of the need to sit or lie down when symptoms of lowered blood pressure occur, although these symptoms are not always orthostatic, and to be careful when rising from a sitting or lying position. In three placebo-controlled BPH studies 1, 2, and 3 (see In multiple dose clinical trials involving nearly 2000 hypertensive patients treated with terazosin, syncope was reported in about 1% of patients.

If blood is pumped too forcefully, or if the blood vessels are too narrow, the pressure of the blood against the walls of the vessels rises.If high blood pressure is not treated, over time, the increased pressure can damage blood vessels or it can cause the heart to work too hard and may decrease the flow of blood to the heart, brain and kidneys. Terazosin Capsules, USP for oral ingestion are supplied in four dosage strengths containing terazosin hydrochloride equivalent to 1 mg, 2 mg, 5 mg, or 10 mg of terazosin.