doi: 10.1176/appi.ajp.2011.11101488.
2012 Jan;169(1):7-9. doi: 10.1176/appi.ajp.2011.11101488.Am J Psychiatry. eCollection 2020.Danielsson B, Collin J, Nyman A, Bergendal A, Borg N, State M, Bergfeldt L, Fastbom J.BMJ Open. Atypon
report is one of the few to have systematically compared mortality risk between different atypical antipsychotic agents.
Wiley
The relative risk of death in patients treated with antipsychotics compared to control patients was 2.354 (95% CI 1.704-3.279). OBJECTIVE: The use of antipsychotics to treat the behavioral symptoms of dementia is associated with greater mortality.
There should be adequate counselling of the patient/family, an explicit risk-benefit analysis and regular review. These data …
2014 Feb;34(1):109-23. doi: 10.1097/JCP.0b013e3182a6096e.BMC Med Res Methodol.
Antipsychotic Agents; Grant Support
Unable to load your delegates due to an error Importance As many as 60% of patients with Parkinson disease (PD) experience psychosis, 80% develop dementia, and the use of antipsychotics (APs) in the population with PD is common. These drugs are the cause for more than 100.000 mortalities. Epub 2019 Dec 2.Sci Rep. 2019 Nov 14;9(1):16856. doi: 10.1038/s41598-019-53057-w. Antipsychotics and mortality in dementia. The current NICE recommendations are that antipsychotics should only be prescribed to those with severe BPSD after exploring other possible interventions. A total of 25.4% of the dementia patients received antipsychotics compared with 4.3% of the controls (OR crude: 7.61; 95%CI: 6.52–8.87). Please enable it to take advantage of the complete set of features!
Name must be less than 100 characters The majority of the participants using antipsychotics used traditional antipsychotics, and traditional antipsychotics were also more frequently used by participants with dementia than by participants without dementia at all time-points. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2020 Jul 31;11:1168. doi: 10.3389/fphar.2020.01168. 2007 Jun 5;146(11):775-86. doi: 10.7326/0003-4819-146-11-200706050-00006. There was no evidence of … Piersanti M, Capannolo M, Turchetti M, Serroni N, De Berardis D, Evangelista P, Costantini P, Orsini A, Rossi A, Maggio R.Riv Psichiatr. 2009 Feb;8(2):151-7. doi: 10.1016/S1474-4422(08)70295-3. doi: 10.1176/appi.ajp.2011.11030347. Wiley
METHOD: The authors conducted a retrospective cohort study using national data from the U.S. Department of … The prevalence of use of antidepressants was approximately 16% at A1, and 22% at A3. The effect of adjusting for these indices in addition to propensity scores (PSs) on the association between antipsychotic medication and mortality was evaluated using Cox models with and without adjustment for risk scores.
They are also frequently used in patients being admitted with pneumonia; however, there are few safety data.
2012 Jan;169(1):71-9. doi: 10.1176/appi.ajp.2011.11030347.
2015 May;72(5):438-45. doi: 10.1001/jamapsychiatry.2014.3018.J Am Geriatr Soc. Am J Psychiatry. 2016 Nov;64(11):2400. doi: 10.1111/jgs.14506. 2013 Dec;33(6):753-8. doi: 10.1097/JCP.0b013e3182a412d5.J Clin Psychopharmacol. doi: 10.1176/appi.ajp.2011.11101488. 2014 Jul;37(7):501-20. doi: 10.1007/s40264-014-0170-y.Harrison SL, Bradley C, Milte R, Liu E, Kouladjian O'Donnell L, Hilmer SN, Crotty M.BMC Geriatr. Atypon Each case was matched to all eligible controls at the date of death by age and duration of dementia. Epub 2010 Aug 5.Psychogeriatrics. Free PMC article 2016 Feb;64(2):299-305. doi: 10.1111/jgs.13943.