{* traditionalSignIn_emailAddress *} A slight delay in ossification was noted in fetuses at the 200 mg/kg dose level and was related to evidence of maternal toxicity. Azithromycin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Azithromycin breastmilk concentrations were measured in 20 women after receiving a single 2 g oral dose of azithromycin during labor. Over the course of a week, approximately 6% of the administered dose appears as unchanged drug in urine.Azithromycin pharmacokinetics was investigated in 42 adults (21 to 85 years of age) with varying degrees of renal impairment. Azithromycin has been linked to rare instances of acute liver injury. For the 594 patients analyzed in the modified intent to treat analysis at the Day 10 visit, the clinical cure rate for 3 days of azithromycin was 88% (268/303) compared to 85% (248/291) for 10 days of amoxicillin/clavulanate. Azithromycin should not be used in patients with pneumonia who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors such as any of the following:To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZITHROMAX (azithromycin) and other antibacterial drugs, ZITHROMAX (azithromycin) should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.

{* #tradAuthenticateMergeForm *} Each patient received active drug and placebo matched for the comparator.For the 366 patients who were evaluated for clinical efficacy at the Day 12 visit, the clinical success rate (i.e., cure plus improvement) was 83% for azithromycin and 88% for the control agent. Potentially serious adverse reactions of angioedema and cholestatic jaundice were reported. In the event of overdosage, general symptomatic and supportive measures are indicated as required.Azithromycin tablets, USP contain the active ingredient azithromycin, USP a macrolide antibacterial drug, for oral administration. Pfizer reconnaît les préoccupations du grand public concernant la situation liée à la COVID-19, qui continue d'évoluer. {* forgotPassword_sendButton *} Sorry, you need to enable JavaScript to visit this website. Available for Android and iOS devices. There may be new information.

These effects were not observed in a pre- and postnatal rat study when up to 200 mg/kg/day of azithromycin was given orally beginning on day 15 of pregnancy until weaning.Advise women to monitor the breastfed infant for diarrhea, vomiting, or rash.Azithromycin breastmilk concentrations were measured in 20 women after receiving a single 2 g oral dose of azithromycin during labor. Your login attempt failed. This third-party website is neither owned nor controlled by Pfizer, and Pfizer does not endorse and is not responsible for the content or services of this site{* message_confirmTraditionalInformation *} {* message_alreadyHaveAccount *} {* backButton *} {* traditionalSignIn_signInButton *} Links to sites outside of Pfizer Medical Information are provided as a resource to the viewer. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in response between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.Elderly patients may be more susceptible to development of torsades de pointes arrhythmias than younger patients.