0000123817 00000 n 0000112098 00000 n 0000118879 00000 n 0000113881 00000 n 0000123992 00000 n 0000114866 00000 n 0000123653 00000 n Y�1�Q���(���>���=��wQk��1�� U�u\C n�71�\��yod�|,��d���,��� 0000110037 00000 n 0000116144 00000 n 0000110170 00000 n 0000115134 00000 n 0000117002 00000 n 0000122939 00000 n 0000108003 00000 n 0000120059 00000 n endstream endobj 464 0 obj <>/CIDToGIDMap /Identity/DW 401/FontDescriptor 466 0 R/Subtype /CIDFontType2/Type /Font/W [0 [778 0 250 250 500 556 667 722 722 722 667 611 889 722 722 722 722 333 722 444 500 444 500 333 278 278 278 500 389 500 778 500 250 500 500 500 500 500 500 500 444 667 556 333 500 333 611 500 250 500 611 0000125988 00000 n 0000007377 00000 n The number of patients treated for 6 months or longer was 3357, and 1350 patients were treated for at least 1 year.In the placebo-controlled clinical trials for Levitra film-coated tablets and vardenafil orally disintegrating tablets, the discontinuation rate due to adverse events was 1.9% for vardenafil compared to 0.8% for placebo.The following section identifies additional, less frequent adverse reactions (<2%) reported during the clinical development of Levitra film-coated tablets and vardenafil orally disintegrating tablets. 0000107899 00000 n 0000118346 00000 n 0000109153 00000 n 0000119058 00000 n It is recommended not to exceed a single 2.5 mg Levitra dose in a 24-hour period when used in combination with indinavir.Ritonavir (600 mg b.i.d.)
0000120808 00000 n �P��2T�m�z�fQK�Ax��2���T��6(�0d�S��`Ȉ�SK /��7�;�/�`�T�{�Rɳ��5��6�귰ϛ? 0000117471 00000 n trailer <>startxref 0 %%EOF 448 0 obj <> endobj 449 0 obj <> endobj 587 0 obj <> stream ��j�A�5�7>6��o]�� �y�U�w����#*���?�-&u�?�뢿G� �A���Y�}��G�b-�"^�@�zO }#� 2�ÄM�G3<\|?δp�U[���V�y(�f��|8Iy���a�r7 0000124891 00000 n 0000125178 00000 n 447 0 obj <> endobj xref 447 141 0000000016 00000 n 0000010617 00000 n
Levitra (vardenafil) is a prescription medication used to treat impotence (or erectile dysfunction, ED, the inability to attain or maintain a penile erection).
0000119647 00000 n Important Information. 0000120967 00000 n 0000108857 00000 n 0000115610 00000 n 0000109314 00000 n LEVITRA Product Monograph Page 1of 52 PRODUCT MONOGRAPH ... (See WARNINGS AND PRECAUTIONS, DOSAGE AND ADMINISTRATION, and ACTION AND CLINICAL PHARMACOLOGY.) It is not possible to determine whether these reported events are related directly to the use of vardenafil, to the patient’s underlying risk factors for Concomitant use of Levitra and nitrates and nitric oxide donors is contraindicated. Some causes of impotence are medically treatable and...Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection. A 5-mg Levitra dose should not be exceeded in a 24-hour period when used in combination with 200 mg once daily ketoconazole. 0000117288 00000 n Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency or establish a causal relationship to drug exposure.Cases of sudden decrease or loss of hearing have been reported postmarketing in temporal association with the use of PDE5 inhibitors, including vardenafil. 0000065933 00000 n Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. 0000123201 00000 n 0000065910 00000 n 0000126732 00000 n Over 2200 patients were treated for 6 months or longer and 880 patients were treated for at least 1 year.In placebo-controlled clinical trials, the discontinuation rate due to adverse events was 3.4% for Levitra compared to 1.1% for placebo.When Levitra was taken as recommended in placebo-controlled clinical trials, the following adverse reactions were reported (see Table 1).Placebo-controlled trials suggested a dose effect in the incidence of some adverse reactions (Levitra film-coated tablets and vardenafil orally disintegrating tablets have been administered to over 17,000 men (mean age 54.5, range 18.89 years; 70% White, 5% Black, 13% Asian, 4% Hispanic and 8% Other) during controlled and uncontrolled clinical trials worldwide.
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0000120256 00000 n Learn about erectile dysfunction causes and treatments such as drugs...Did you know that certain medical condition may be responsible for ED? 0000119821 00000 n 0000108516 00000 n 0000112523 00000 n
The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis. 0000118048 00000 n 0000122101 00000 n 0000112348 00000 n 0000006277 00000 n 0000113405 00000 n Excluded from this list are those adverse reactions that are infrequent and minor, those events that may be commonly observed in the absence of drug therapy, and those events that are not reasonably associated with the drug:The following adverse reactions have been identified during post approval use of Levitra. 0000003294 00000 n 0000112220 00000 n