67457-814-00, In life-threatening situations due to either aerobes or anaerobes these doses may be increased. Take the capsule with a full glass of water to keep it from irritating your throat. Multiple entries with a needle and syringe are not recommended. See Single intramuscular injections of greater than 600 mg are not recommended.Alternatively, drug may be administered in the form of a single rapid infusion of the first dose followed by continuous IV infusion as follows:Parenteral therapy may be changed to clindamycin palmitate hydrochloride for oral solution or clindamycin hydrochloride capsules when the condition warrants and at the discretion of the physician.In cases of β-hemolytic streptococcal infections, treatment should be continued for at least 10 days.Administration of more than 1200 mg in a single 1-hour infusion is not recommended.Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.The following drugs are physically incompatible with clindamycin phosphate: ampicillin sodium, phenytoin sodium, barbiturates, aminophylline, calcium gluconate, and magnesium sulfate.The compatibility and duration of stability of drug admixtures will vary depending on concentration and other conditions. 0000001416 00000 n Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. To reduce the development of drug-resistant bacteria and maintain the effectiveness of clindamycin hydrochloride capsules and other antibacterial drugs, clindamycin hydrochloride capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.Because clindamycin hydrochloride therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the If CDAD is suspected or confirmed, ongoing antibiotic use not directed against Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin.

0000006373 00000 n Due to inconsistencies between the drug labels on DailyMed and the pill images provided by 0000002660 00000 n In the mice, convulsions and depression were observed.Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum.If diarrhea occurs during therapy, this antibiotic should be discontinued (see More severe infections, particularly those due to proven or suspected For more serious infections, these doses may have to be increased. If you are a consumer or patient please visit They do not treat viral infections (e.g., the common cold). , patients with recent Clindamycin is bacteriostatic.Resistance to clindamycin is most often caused by modification of specific bases of the 23S ribosomal RNA. In the presence of strong CYP3A4 inducers such as rifampicin, monitor for loss of effectiveness.Long-term studies in animals have not been performed with clindamycin to evaluate carcinogenic potential. See The potential for the toxic effect in the pediatric population from chemicals that may leach from the single dose premixed IV preparation in plastic has not been evaluated. trailer Because of the risk of antibiotic-associated pseudomembranous colitis, as described in the Bacteriologic studies should be performed to determine the causative organisms and their susceptibility to clindamycin.Indicated surgical procedures should be performed in conjunction with antibiotic therapy.Clindamycin injection is indicated in the treatment of serious infections caused by susceptible strains of the designated organisms in the conditions listed below:Lower respiratory tract infections including pneumonia, empyema, and lung abscess caused by anaerobes, Gynecological infections including endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection caused by susceptible anaerobes.Intra-abdominal infections including peritonitis and intra-abdominal abscess caused by susceptible anaerobic organisms.Bone and joint infections including acute hematogenous osteomyelitis caused by To reduce the development of drug-resistant bacteria and maintain the effectiveness of clindamycin injection and other antibacterial drugs, clindamycin injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. clindamycin HCl 150 mg capsule. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Pediatric: 10-20 mg/kg/day orally divided every 6-8 hours, OR . In the mice, convulsions and depression were observed.Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum.If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see To avoid the possibility of esophageal irritation, clindamycin hydrochloride capsules should be taken with a full glass of water.Clindamycin hydrochloride capsules are not suitable for children who are unable to swallow them whole. 0000001609 00000 n 0000009771 00000 n