Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. CERTIFICATE This is to Certify that the dissertation entitled “FORMULATION AND EVALUATION OF FEXOFENADINE HYDROCHLORIDE FILM COATED TABLETS” is a bonafide and genuine research … In objective tests, fexofenadine has been shown to have no significant effects on central nervous system function. Fexofenadine at concentrations 32 times greater than the therapeutic concentration in man had no effect on the delayed rectifier KFexofenadine hydrochloride (5-10 mg/kg per orally) inhibited antigen induced bronchospasm in sensitised guinea pigs and inhibited histamine release at supra- therapeutic concentrations (10- 100 µM) from peritoneal mast cells.Fexofenadine hydrochloride is rapidly absorbed into the body following oral administration, with TFexofenadine undergoes negligible metabolism (hepatic or non-hepatic), as it was the only major compound identified in urine and faeces of animals and man. There is no evidence of tolerance to these effects after 28 days of dosing. The score line is only to facilitate breaking for ease of swallowing and not to divide into equal doses.Fexofenadine hydrochloride 180 mg tablet is indicated in adults and children 12 years and older for the relief of symptoms associated with chronic idiopathic urticaria.The recommended dose of fexofenadine hydrochloride for adults is 180 mg once daily taken before a meal.Fexofenadine is a pharmacologically active metabolite of terfenadine.The recommended dose of fexofenadine hydrochloride for adolescents aged 12 years and over is 180 mg once daily taken before a meal.The efficacy and safety of fexofenadine hydrochloride 180 mg has not been studied in children under 12.Studies in special risk groups (elderly, renally or hepatically impaired patients) indicate that it is not necessary to adjust the dose of fexofenadine hydrochloride in these patients.Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.As with most new medicinal products there is only limited data in the elderly and renally or hepatically impaired patients.Fexofenadine hydrochloride should be administered with care in these special groups.Patients with a history of or ongoing cardiovascular disease should be warned that, antihistamines as a medicine class, have been associated with the adverse reactions, tachycardia and palpitations (see section 4.8).This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free.
Fexofenadine is an antihistamine that is used to treat the symptoms of seasonal Fexofenadine is also used to treat skin itching and There are many brands and forms of fexofenadine available. Therefore fexofenadine hydrochloride is not recommended for mothers breast-feeding their babies.No human data on the effect of fexofenadine hydrochloride on fertility are available. Single doses up to 800 mg, and doses up to 690 mg twice daily for 1 month, or 240 mg once daily for 1 year have been administered to healthy subjects without the development of clinically significant adverse reactions as compared with placebo. The objective of this research work was to mask the intense bitter taste of fexofenadine hydrochloride using weak cation exchange resins and to formulate orodispersible tablet of taste masked drug-resin complex. Do not use two doses at one time.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Do not take fexofenadine with fruit juice (such as apple, orange, or grapefruit). However, when terfenadine was administered to nursing mothers fexofenadine was found to cross into human breast milk. A positive dose-response relationship between doses of 10 mg to 130 mg taken orally was found to exist. Prof. Dr.K.Senthilkumaran M.Pharm., Ph.D., Head of Department Department of Pharmaceutics K.K.College of Pharmacy Chennai - 60012 .
Version: 11.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The Tamil Nadu Dr. M.G.R Medical University, Chennai – 32. Symptomatic and supportive treatment is recommended. Tell your doctor if you have Use exactly as directed on the label, or as prescribed by your doctor.Always follow directions on the medicine label about giving cough or cold medicine to a child.Ask a doctor before giving fexofenadine liquid to a child younger than 2 years old.The disintegrating (melting) tablets are not for use in a child younger than 6 years old.The 12-hour and 24-hour forms of fexofenadine are not for use in a child younger than 12 years old.Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. 4.4 Special warnings and precautions for use. Maximum inhibition in skin wheal and flare areas was greater than 80%. This site uses cookies. फेक्सोफेनाडाइन हाइड्रोक्लोराइड / Fexofenadine Hydrochloride मौसमी प्रत्यूर्जतात्मक नासाशोध, जीर्ण अज्ञातहेतुक पित्ती और अन्य स्थितियों के उपचार के लिए निर्देशित क� Instruct patients to take Fexofenadine hydrochloride tablets only as prescribed.