But is this really necessary with Azathioprine? Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Take this medicine exactly as directed by your doctor. We comply with the HONcode standard for trustworthy health information - Taking this medicine after meals, in divided doses, or at bedtime may lessen stomach upset. If you are using several medicines together, make sure you understand how to take them during the day.

TPMT helps to break down and remove azathioprine from the body. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. The amount of medicine that you take depends on the strength of the medicine.

It suppresses the immune system by interfering with DNA synthesis (the creation of DNA molecules). Concomitant allopurinol: Azathioprine dose should be reduced to 25% to 33% of the usual dose. The following information includes only the average doses of this medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 am and 3 pm Avoid sunlamps and tanning beds.

Follow your doctor's orders or the directions on the label. Tomorrow I'm going to drop to 75 mg/day for a month, then reducing by 25 mg/day every month until I'm off.

Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. The following information includes only the average doses of this medicine.

Azathioprine (Imuran) is a drug used in certain autoimmune conditions (diseases where the body’s natural defense system attacks itself). Taking too much may increase the chance of unwanted effects, and taking too little will not help your condition. While you are being treated with azathioprine, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Do not double doses.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine is sometimes given together with other medicines. 1 mg/kg/day IV/PO initially in single daily dose or divided q12hr; may be increased by 0.5 mg/kg/day after 6-8 weeks, then by 0.5 mg/kg/day every 4 weeks; not to exceed 2.5 mg/kg/day . Talk to your doctor if you have questions or continue to have problems with nausea or vomiting. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Low levels of TPMT may mean there is a slightly increased risk of side effects from azathioprine, so your doctor may suggest a lower dose. Follow your doctor's orders or the directions on the label.

© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. All rights reserved. Dose reduction to maintenance levels of 1 to 3 mg/kg daily is usually possible. My GI also kept me on my standard 175 mg/day of Azathioprine, which he finally had me reduce down to 125 mg/day last month. Applies to the following strengths: 50 mg; 100 mg; 75 mgInitial dose: 3 to 5 mg/kg orally or IV once a day, beginning at the time of transplantInitial dose: 1 mg/kg (50 to 100 mg) orally or IV per day given in 1 to 2 divided dosesInitial dose: 3 to 5 mg/kg orally or IV once a day, beginning at the time of transplantLower doses may be required; however, no specific guidelines have been suggested.Dose adjustments may be required; however, no specific guidelines have been suggested.Dosage reduction or alternative therapy may be required in patients with reduced thiopurine S-methyltransferase (TPMT) activity.Data not available; approximately 45% of an azathioprine dose is removed by hemodialysis.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not stop using this medicine without first checking with your doctor.

Dosage reduction or alternative therapy may be required in patients with reduced thiopurine S-methyltransferase (TPMT) activity. Ask your doctor to help you plan a way to remember to take your medicines at the right times. The dose of this medicine will be different for different patients. Further dose reduction or alternative therapies should be considered for patients with low or absent TPMT activity.

If your dose is different, do not change it unless your doctor tells you to do so.

Your doctor may do blood tests, lower your dosage of azathioprine, or stop your treatment with the medication. Azathioprine sometimes causes nausea or vomiting.