Pharmacia and Upjohn, Kalamazoo, MI. Br J Pharmacol 59 (1977): 433-442. Fukutomi T, Nanasawa T, Yamamoto H, Adachi I, Watanabe T "The induction of a hypercoagulable state by medroxyprogesterone acetate in breast cancer patients." Jordan A "Toxicology of depot medroxyprogesterone acetate." Am J Obstet Gynecol 114 (1972): 97-10224. Am J Obstet Gynecol 170 (1994): 1543-910. Fertil Steril 23 (1972): 489-9230. Jpn J Surg 20 (1990): 665-7032. Read More Side Effects of Januvia (Sitagliptin) of Short term and Long term. O 07. Your cancer doctor or nurse can explain the risk of these side effects … Cerner Multum, Inc. "UK Summary of Product Characteristics." WHO Collaborative Study of Neoplasia and Steroid Contraceptives" Lancet 2 (1984): 1207-855. Drug information provided by: IBM Micromedex. Contraception 49 (1994): 211-2261.

Grenfell A, Rudenski A, Watts M, Wiltshire C, Day JL, Gray IP "Cushing's syndrome and medroxyprogesterone acetate" Lancet 336 (1990): 25643.

Cundy T, Evans M, Roberts H, Wattie D, Ames R, Reid IR "Bone density in women receiving depot medroxyprogesterone acetate for contraception [published erratum appears in BMJ 1991 Jul27;303(6796):220]." If experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionSelected from data included with permission and copyrighted by First Databank, Inc. Int J Gynaecol Obstet 24 (1986): 291-623. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Serious and life-threatening side effects.

Sapire KE "A study of bleeding patterns with two injectable contraceptives given postpartum and the effect of two non-hormonal treatments." "Breast cancer and depot-medroxyprogesterone acetate: a multinational study. "Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial." Oberle MW, Rosero-Bixby L, Irwin KL, Fortney JA, Lee NC, Whatley AS, Bonhomme MG "Cervical cancer risk and use of depot-medroxyprogesterone acetate in Costa Rica." A subset of these reports involved patients with renal insufficiency, some who were prescribed inappropriate doses of this drug. JAMA 273 (1995): 799-80760. The unwanted effects may … Contraception 49 (1994): 223-3051. With drug discontinuation, supportive treatment and discontinuation of potentially causative agents, a return to baseline levels of renal insufficiency occurred.Between October 2006 and December 2013, thirty-three cases of severe arthralgia have been reported to the FDA Adverse Event Reporting System Database. A positive rechallenge was reported in 8 cases, with 6 cases involving use of a different DPP-4 inhibitor. Virutamasen P, Wongsrichanalai C, Tangkeo P, Nitichai Y, Rienprayoon D "Metabolic effects of depot-medroxyprogesterone acetate in long-term users: a cross-sectional study." Conception and contraception. Available from: URL: http://www.fda.gov/downloads/Drugs/DrugSafety/UCM460038.pdf." O 05. Contraception 58 (1998): 351-536. It works by increasing the amount of incretin released by the intestine. How it works . In all cases, substantial reduction in prior activity level was reported, 10 patients were hospitalized due to disabling joint pain. Hormones are natural substances made by glands in our bodies. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Sitagliptin (the active ingredient contained in Januvia) had the greatest number of cases reported (n=28) followed by The most commonly reported adverse events included 1. Greenstone LLC, Peapack, NJ. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.

Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Some side effects may occur that usually do not need medical attention. The WHO Collaborative Study of Neoplasia and Steroid Contraceptives." Contraception 22 (1980): 605-2221. You will find a full list in the manufacturer's information leaflet that has been given to you. Task Force on Long-Acting Systemic Agents for Fertility Regulation." Available for Android and iOS devices.