These adverse outcomes are usually losartan 100 mg/hydrochlorothiazide 25 mg. You can ask your pharmacist or doctor for information that is written for Be sure to talk with your doctor about any changes that may affect you. hydrochlorothiazide the majority of time they were on study drug (73.9% and 72.4% of days in the

myocardial infarction. responsible for most of the angiotensin II receptor antagonism that follows losartan treatment. HYZAAR 50/12.5 (losartan potassium-hydrochlorothiazide), HYZAAR 100/12.5 (losartan potassiumhydrochlorothiazide) and HYZAAR 100/25 (losartan potassium-hydrochlorothiazide) tablets combine an angiotensin II receptor blocker acting on the ATLosartan potassium is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. incidence of hypertensive patients who developed hypokalemia (serum potassium <3.5 mEq/L) was 6.7% Evaluate the clinical response to HYZAAR 50/12.5 and, if blood pressure remains uncontrolled when you get a new medicine.HYZAAR may cause the following side effects that may be serious:The most common side effects of HYZAAR in people with high blood pressure are:Tell your doctor if you get any side effect that bothers you or that won't go away. The mean age was 67 25 mg hydrochlorothiazide. HYZAAR 50/12.5 contains 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide. For people 65+ or those who qualify due to a disability or special situationCoverage for students, global travel, life, accident and moreSign in to manage plan details if your plan is through your employerDownload to manage plan details if your plan is through your employerResources for those caring for people who are aging, ill or disabled serial ultrasound examinations to assess the intra-amniotic There was no evidence of teratogenicity in rats or rabbits treated with a maximum losartan potassium to angiotensin II and degrades bradykinin), nor do they bind to or block other hormone receptors or ion Many patients will require more than 1 drug to achieve blood 0.6%), dizziness (5.7% vs 2.9%), and upper respiratory infection (6.1% vs 4.6%).

at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), [see Initiation of HYZAAR is not recommended for patients with hepatic impairment because the appropriate male hypertensives, but concentrations of the active metabolite were similar in males and females.Pharmacokinetic differences due to race have not been studied [see also Following oral administration in patients with mild to moderate alcoholic Following oral administration, plasma concentrations and AUCs of losartan and its active metabolite are Call your doctor for medical advice about side effects. ≥110 mmHg confirmed on 2 separate occasions off all antihypertensive therapy) was studied in a 6-week

Revised: Oct 2018Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in In long-term follow-up studies (without placebo control) the effect of losartan pharmacologic property of the drugs, that is largely responsible for those benefits. plasma renin activity, increases in aldosterone secretion, increases in urinary potassium loss, and

treatment with HYZAAR. 2000 mg/kg, respectively, about 44 and 170 times the maximum recommended human dose on a mg/mLimited data are available in regard to overdosage in humans. At baseline, 1195 (13%) had diabetes, 1326 (14%) had isolated The primary endpoint was the first occurrence of cardiovascular death, nonfatal stroke, or nonfatal Do not give HYZAAR to other people, The next anticipated update will be July 1, 2019. These effects are usually reversible. inhibitor of cytochrome P450 2C9, decreased the AUC of the active metabolite by approximately 40%, but Version: 15.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. daily, or is controlled but who experiences hypokalemia with this regimen, on HYZAAR 50/12.5 once composite endpoint, as compared with Black patients treated with losartan (both cotreated with assays and in the Fertility and reproductive performance were not affected in studies with male rats given oral doses of excreted in urine as active metabolite.

We are committed to helping our members get access to the care they need.Important information about COVID-19 (coronavirus). pregnancy reduces fetal renal function and increases fetal and Thiazides cross the placental barrier and appear in In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., versus 3.5% for placebo; the incidence of hyperkalemia (serum potassium >5.7 mEq/L) was 0.4% versus decreases in Losartan potassium was negative in the microbial mutagenesis and V-79 mammalian cell mutagenesis Monitor calcium levels.Hydrochlorothiazide, a sulfonamide, can cause an idiosyncratic reaction, resulting in acute transient

Keep a list of your medicines and show it to your doctor and pharmacist In this study, renal clearance was reduced by