This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment. Side effects include abdominal cramping and pain, flatulence (farting), and fatty or oily stools.

03 Aug 2020 Acarbose, which acts on intestinal glucosidase enzymes, should not be prescribed with orlistat as the potential for interactions has not been studied.Pooled data have revealed more cases of breast cancer in women taking orlistat than in those taking a placebo. On the basis of reports from literature 1 … Most of the approximately 9% of patients who discontinued treatment because of adverse effects did so because of gastrointestinal problems.Although orlistat reduces cholesterol concentrations, it also reduces the absorption of fat-soluble vitamins. Orlistat is a potent, specific, and long-acting inhibitor of gastrointestinal lipases.

06 Aug 2020

One approach is to stop orlistat if the patient has not lost 5% of their weight after 12 weeks of treatment.

02 Sep 2020

09 Jun 2020

Orlistat may reduce absorption of some fat-soluble vitamins and beta-carotene; Instruct patient to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition; Take vitamin supplement at least 2 hr before or after taking orlistat, such as at bedtime Orlistat increases the plasma concentration of pravastatin, but does not alter the pharmacokinetics of digoxin, glibenclamide or phenytoin.

Reduced vitamin K absorption could alter the control of patients taking warfarin. This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. Particular care should be taken with antiepileptics, antiretrovirals, and drugs that have a narrow therapeutic index.