Wiley The rate of absorption is not affected by age.

1995 Dec;8(6):491-512. doi: 10.2165/00019053-199508060-00005.Drugs. 1987 Nov;20 Suppl B:89-100. doi: 10.1093/jac/20.suppl_b.89.Lam YW, Flaherty JF, Yumena L, Schoenfeld PY, Gambertoglio JG.J Antimicrob Chemother. Peak plasma levels following 150- and 300-mg doses occur within two hours. About 10% of the dose is excreted in urine.

Peak plasma levels following 150- and 300-mg doses occur within two hours.

This report contains the findings of five studies performed to evaluate the pharmacokinetics of roxithromycin (RU 965), a new macrolide antibiotic.

doi: 10.1136/bmj.g1908.Pharmacoeconomics. 2014 Mar 11;348:g1908.

doi: 10.1002/j.1552-4604.1988.tb05738.x. Although dose dependency was observed for the various pharmacokinetic parameters, dose proportionality could be demonstrated only in terms of the percentage of the dose excreted in urine.

Pharmacokinetics. The drug is rapidly absorbed after oral administration.

The rate of absorption is not affected by age. Unable to load your collection due to an error

J Antimicrob Chemother.

When taken before a meal, roxithromycin is very rapidly absorbed, and diffuses into most tissues and phagocytes.
The rate of elimination and renal clearance are decreased in healthy elderly subjects, however, these differences should not be clinically meaningful. Please enable it to take advantage of the complete set of features! 1989 Aug;29(8):752-6. doi: 10.1002/j.1552-4604.1989.tb03412.x.J Antimicrob Chemother. Although dose dependency was observed for the various pharmacokinetic parameters, dose proportionality could be demonstrated only in terms of the percentage of the dose excreted in urine.

This report contains the findings of five studies performed to evaluate the pharmacokinetics of roxithromycin (RU 965), a new macrolide antibiotic. 1995 Jul;36(1):157-63. doi: 10.1093/jac/36.1.157.Antimicrob Agents Chemother. Roxithromycin was safe and well tolerated with no clinically meaningful changes in any of the safety variables in any of the five studies reported.

The plasma half-life is approximately 12 hours. doi: 10.1002/j.1552-4604.1988.tb05738.x. doi: 10.1136/bmj.g1908.Pharmacoeconomics.

Peak plasma levels following 150‐ and 300‐mg doses occur within two hours. Due to the high concentration in phagocytes, roxithromycin is actively transported to the site of infection.



Unable to load your collection due to an error Pharmacokinetics of roxithromycin (RU 965) This report contains the findings of five studies performed to evaluate the pharmacokinetics of roxithromycin (RU 965), a new macrolide antibiotic.

1996 Apr;51(4):515-36. doi: 10.2165/00003495-199651040-00002.Karalus NC, Garrett JE, Lang SD, Leng RA, Kostalas GN, Cursons RT, Cooper BC, Ryan CJ.Infection. The drug is rapidly absorbed after oral administration.

Roxithromycin was given as 150- and 300-mg film-coated tablets. Steady state is reached within four days with doses of 150 mg twice a day …


2014 Mar 11;348:g1908. During active phagocytosis, large concentrations of roxithromycin are released.

Wiley 1996 Apr;51(4):515-36. doi: 10.2165/00003495-199651040-00002.Karalus NC, Garrett JE, Lang SD, Leng RA, Kostalas GN, Cursons RT, Cooper BC, Ryan CJ.Infection. 1987 Jul;31(7):1051-3. doi: 10.1128/aac.31.7.1051.J Antimicrob Chemother. Unable to load your delegates due to an error Roxithromycin was given as 150- and 300-mg film-coated tablets. This site needs JavaScript to work properly.



1995 Dec;8(6):491-512. doi: 10.2165/00019053-199508060-00005.Drugs.