), cyproheptadine (2 mg, b.i.d. From two years I am also suffering from high pulse rate 95 to 100/minute, over weight 95 KG, low sex drive, belly fat , weakness,Muscle spasm, … within 2 years – resulting in a total gain of ~6.61 lbs. Guidelines for migraine treatment in 2013 and mentioned that while propranolol is associated with weight gain – exact rates of weight gain among propranolol users haven’t been determined. increased body fat, loss of lean mass, etc.

The patient was prescribed propranolol (80 mg, b.i.d.) It's been about 2 months and I have gained around 6lbs.

Results indicated that: after 1 year of treatment, 27% of propranolol recipients (450/1679) and 21% of placebo recipients (350/1648) exhibited After 1 year of treatment propranolol recipients exhibited greater average Following the second year of treatment, average weight gain from baseline was It was concluded that long-term beta blockade yields significant and sustained weight gain. As a non-selective beta blocker, propranolol prevents endogenous catecholamines (e.g. Other studies with large sample sizes conducted by Rao et al.

Results of the review indicated that propranolol is associated with varying degrees of weight gain.That said, weight gain seems to be more prevalent with amitriptyline and divalproex than propranolol. A large-scale randomized controlled trial by Diener et al. Applies to propranolol: oral capsule extended release, oral solution, oral tabletOther dosage forms: 1. intravenous solutionAlong with its needed effects, propranolol may cause some unwanted effects.

Burning fewer total calories per day and exhibiting a slower metabolic rate (than before using propranolol) due to fatigue could lead to significant weight gain – especially if you’re consuming the same number of calories (as you did pre-treatment).Perhaps an increase in pathogenic bacteria could: stimulate appetite, cause food cravings, increase fat storage, and/or decrease resting metabolic rate. also demonstrated a major role of the β 1-receptor in the sympathetic stimulation of BAT thermogenesis in response to cold exposure and high-fat feeding [24]. Weight gain on propranolol? Other research by Murakami et al.

In any regard, this review supports the idea that Maggioni, Ruffatti, Dainese, et al. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking propranolol:

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slowing of metabolic rate, decreased exercise tolerance, increased appetite) – leading to greater weight gain than you would’ve experienced with standalone propranolol.A variety of individual factors could also determine which propranolol users are likely to gain a significant amount of weight. Hyperthyroidism-induced weight loss subsided in patients who exhibited significant reductions in serum T3 (attributable to propranolol therapy); this was In patients with hypothyroidism, the combination of propranolol plus thyroxine increased T3 to a greater extent than standalone thyroxine therapy, which led to weight loss. The aim of the study was to determine whether one medication (propranolol or flunarizine) might be more effective and/or tolerable than the other.A total of 94 patients (diagnosed with migraine) were recruited to participate in the study and assigned randomly to receive: propranolol (80 mg, b.i.d.)

While reading the explanations below, it is necessary to understand that the mechanism(s) by which propranolol causes weight gain aren’t fully understood – and may be subject to interindividual variation.If your appetite increases while using propranolol, this could definitely lead you to consume more food (i.e. (Hypothetical answers might include things like: hormonal alterations; appetite increase; fatigue (making it difficult to exercise); slowed metabolism; reversed my hyperthyroidism; etc. As of current, it seems as though nearly all large-scale studies involving propranolol indicate that weight gain can occur as a side effect – especially when administered over a long-term.Understand that while there may be some limitations associated with the studies below, the data provided by these studies are unambiguous in suggesting that propranolol usage causes weight gain.

Propranolol, sometimes referred to as Inderal (brand name), is a non-cardioselective sympatholytic beta blocker that was first synthesized by British scientist James Black in 1964. If you find that the intensity and/or length of your workouts is reduced, or that you’re unable to tolerate as much exercise while taking propranolol, this could: decrease your energy expenditure, alter your hormones, slow your metabolic rate, modulate your body composition – and cause weight gain.Earlier research by Christin et al.

Although the effect of propranolol on the gut microbiome remains unclear, this could be a mechanism by which the medication promotes weight gain.Additionally, it is thought that propranolol might alter hormones such as: insulin, estrogen, cortisol, prolactin, epinephrine, and norepinephrine. I was curious if this was a common symptom and stumbled upon this thread. If you are unable to control yourself around food (e.g. Available for Android and iOS devices.

The combination of increased body fat storage coupled with muscle loss could deleteriously affect: hormone levels (e.g. norepinephrine and epinephrine) from activating Beta-1 and Beta-2 adrenergic receptors within the CNS (central nervous system) and PNS (peripheral nervous system). It is generally understood that larger doses of propranolol modulate aspects of physiology (e.g. Of the 89 patients who completed 6 months of prophylactic therapy, it was noted that 13 were using propranolol (80-160 mg/day) as a standalone agent. ).In summary, it seems as though significant weight gain (in excess of 5 lbs.)