The most common adverse reactions at the site of topical application were dry lips, desquamation, dryness of skin, cracked lips, burning skin, pruritus, flakiness of skin, and stinging on skin; each adverse reaction occurred in less than 1% of patients receiving Acyclovir Cream and placebo. This medication is used to treat " cold sores / fever blisters " (herpes labialis). It belongs to a group of medicines called “anti-virals”, which act to treat infections caused by viruses. What Aciclovir cream looks like and contents of the pack: These concentrations would potentially expose the nursing infant to a dose of acyclovir up to 0.3 mg/kg/day. It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching). during the prodrome or when lesions appear.For adolescents 12 years of age and older, the dosage is the same as in adults.Each gram of Acyclovir Cream 5% contains 50 mg of acyclovir.Acyclovir Cream is contraindicated in patients with known hypersensitivity to acyclovir, valacyclovir, or any component of the formulation.Acyclovir Cream should only be applied on the affected external aspects of the lips and face in patients with herpes labialis. While making use of acyclovir you can experience several of the side effects: queasiness, throwing up, lightheadedness, headache, puffinessing of your feet or hands.Make certain you speak with your doctor before breastfeeding if you are taking acyclovir. • C ontinue treatment for 4 days. The average patient had five episodes of herpes labialis in the previous 12 months. Do not give Acyclovir Cream to other people, even if they have the same symptoms you have. Both Acyclovir Cream and placebo showed a high and cumulative irritation potential. Store at or below 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Keep out of reach of children.Common skin-related side effects that occurred when Acyclovir Cream was applied include application site reactions. Before you use Acyclovir Cream, tell your doctor if you are pregnant, planning to become pregnant, or are breast-feeding.Treatment should be initiated at the earliest sign or symptom of recurrence. In this trial, therapy was applied using the same dosing regimen as in adults and subjects were followed for adverse events. Teva Cold Sore 5% Cream contains the active ingredient aciclovir. pply liberally to the affected area 5 times a day. Subjects were instructed to initiate treatment within 1 hour of noticing signs or symptoms and continue treatment for 4 days, with application of study medication 5 times per day.

These events have been chosen for inclusion due to a combination of their seriousness, frequency of reporting, or potential causal connection to Acyclovir Cream.Clinical experience has identified no interactions resulting from topical or systemic administration of other drugs concomitantly with Acyclovir Cream. Acyclovir Cream has the potential for irritation and contact sensitization.Before using Acyclovir Cream, tell your healthcare provider about all of your medical conditions, including if you:The most common side effects of Acyclovir Cream are skin reactions at the treatment site and may include: dry or cracked lips, peeling, flaking or dryness of the skin, a burning or stinging feeling, and itching.These are not all the possible side effects of Acyclovir Cream. • The active substance is aciclovir (5% w/w). Each gram of Acyclovir Cream 5% contains 50 mg acyclovir in an aqueous cream base. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Patients should be instructed to topically apply a quantity of Acyclovir Cream sufficient to cover the affected area, including the outer margin. • The other ingredients are cetyl alcohol, dimethicone, heavy liquid paraffin, polyethylene glycol - 5 glyceryl stearate, propylene glycol, sorbic acid, white soft paraffin and water. Another study, enrolling 251 healthy adults, was conducted to evaluate the contact sensitization potential of Acyclovir Cream using repeat insult patch testing methodology. Do not use Acyclovir Cream for a condition for which it was not prescribed. Patients should be advised to avoid unnecessary rubbing of the affected area to avoid aggravating or transferring the infection.

Patients should be advised to apply Acyclovir Cream topically 5 times per day for 4 days. Patients should be instructed to wash hands prior to application and ensure the face and/or lips are clean and dry. Acyclovir Cream 5% is a formulation for topical administration.The chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy) methyl]-6Acyclovir is a white, crystalline powder with the molecular formula CEach gram of Acyclovir Cream 5% contains 50 mg of acyclovir and the following inactive ingredients: cetostearyl alcohol, mineral oil, poloxamer 407, propylene glycol, purified water, sodium lauryl sulfate, and white petrolatum.Acyclovir is an antiviral drug active against herpes simplex virus [see A clinical pharmacology study was performed with Acyclovir Cream in adult volunteers to evaluate the percutaneous absorption of acyclovir.

The safety profile was similar to that observed in adults.Each gram of Acyclovir Cream 5% contains 50 mg acyclovir in an aqueous cream base. You can take Acyclovir with some meals or without, yet constantly in the same means. Select one or more newsletters to continue. Acyclovir therapy need to be started as early as possible after the initial indicators of the infection are shown (scorchings, burning etc), due to the fact that it will be most efficient after that. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. Due to minimal systemic absorption of Acyclovir Cream, systemic drug interactions are unlikely.There are no adequate and well-controlled studies of Acyclovir Cream in pregnant women. Three patients on Acyclovir Cream and one patient on placebo discontinued treatment due to an adverse event.An additional study, enrolling 22 healthy adults, was conducted to evaluate the dermal tolerance of Acyclovir Cream compared with vehicle using single occluded and semi-occluded patch testing methodology. The sensitizing ingredient(s) has not been identified.The safety profile in patients 12 to 17 years of age was similar to that observed in adults.In addition to adverse events reported from clinical trials, the following events have been identified during postapproval use of Acyclovir Cream. In this study, which included 6 male volunteers, the cream was applied to an area of 710 cmThe systemic absorption of acyclovir following topical application of cream has not been evaluated in patients <18 years of age.The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV.