I took Trintellix successfully for almost a year. Below are examples of these side effects.The only condition both Trintellix and Effexor XR are used to treat is MDD. Wellbutrin affects different chemical messengers called norepinephrine and dopamine.Wellbutrin comes as extended-release tablets called Wellbutrin SR and Wellbutrin XL. Some people who take Trintellix can feel restless, energized, or have trouble sleeping soon after they take the medication. The effectiveness of these drugs in treating MDD hasn’t been directly compared in clinical studies. Wellbutrin XL and Wellbutrin SR are available as brand-name drugs as well as in generic forms. However, be sure to take the dosage your doctor prescribes for you.

Trintellix should be stored at room temperature, at about 77º F (25º C).If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.The following information is provided for clinicians and other healthcare professionals.Trintellix has a unique mechanism of action. Wellbutrin SR is approved only for treating MDD.Trintellix comes only as an oral tablet that’s taken once daily. These drugs include aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and others.Trintellix can cause low sodium levels in certain people. Wellbutrin XL is FDA-approved for treating major depressive disorder (MDD) and seasonal affective disorder. No benefits from depression or anxiety Zoloft comes as an oral tablet and an oral solution. The use of Trintellix can increase the risk of suicidal thoughts in children and young adults.Some people who take Trintellix have gained weight while taking the medication. It does this by blocking reabsorption (reuptake) of serotonin.In most cases, people taking Trintellix haven’t reported feeling tired or sleepy. These side effects may go away during treatment as your body adjusts to the medicine. Prozac is available as a brand-name drug and in a generic form called fluoxetine.Generic Prozac is much less expensive than Trintellix. It’s not clear if Trintellix was the cause.Taking too much of this medication can increase your risk of serious side effects.Some symptoms of overdose of Trintellix may include:If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their This drug has a boxed warning. Receptors are like docking stations on cells, and serotonin attaches to them.But when Trintellix blocks these receptors, serotonin can’t attach to them. So after 6 weeks on 20 mg of trintellix nothing but side effects, nausea, crying episodes, and the dreaded itch skin syndrome Upper body mostly. 2. In some cases, this may be due to fluid retention caused by a condition called syndrome of inappropriate antidiuretic hormone. In an Trintellix hasn’t been directly compared to the most commonly used antidepressants, which are called selective serotonin reuptake inhibitors (SSRIs).Trintellix is only approved for treating depression, but it may be used off-label for other conditions. The effectiveness of these drugs in treating MDD hasn’t been directly compared in clinical studies. - at least that has been my experience. Some complications that have occurred include trouble breathing, seizures, irritability, and trouble feeding.It’s also important to keep in mind that stopping treatment with Trintellix in pregnant women with MDD can also have serious consequences. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Some side effects may occur that usually do not need medical attention.