Jonkman JH, van der Boon WJ, Schoenmaker R, Holtkamp AH, Hempenius J.Chemotherapy. When a loading dose becomes necessary in the patient who has already received theophylline, estimation of the serum concentration based upon the history is unreliable, and an immediate serum level determination is indicated. Theophylline is structurally classified as a methylxanthine.

This empiric method, based upon mean pharmacokinetic parameters, will prevent large fluctuations in serum concentration during the most critical period of the patient's course.In patients with cor pulmonale, cardiac decompensation, or liver dysfunction, or in those taking drugs that markedly reduce theophylline clearance (e.g., cimetidine), the initial theophylline infusion rate should not exceed 17 mg/hr (21 mg/hr as aminophylline) unless serum concentrations can be monitored at 24-hour intervals.

In general, these recommendations should serve as the upper limit for dosage adjustments in order to decrease the risk of potentially serious adverse events associated with unexpected large increases in serum theophylline concentration.Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.Theophylline increases the force of contraction of diaphragmatic muscles.

Application of these general dosing recommendations to individual patients must take into account the unique clinical characteristics of each patient. Therefore, it is not recommended that theophylline extended-release once-daily dosing be administered at night.100 mg - White, round, bisected tablets in bottles of 100 and 500.200 mg - White, oval-shaped, bisected tablets in bottles of 100, 500 and 1000.300 mg - White, capsule-shaped, bisected tablets in bottles of 100, 500 and 1000.450 mg - White, capsule-shaped, bisected tablets in bottles of 100, 250 and 500.Dispense in a well-closed container as defined in the USP.National Institutes of Health, U.S. National Library of Medicine, * Approximation only. In general, these recommendations should serve as the upper limit for dosage adjustments in order to decrease the risk of potentially serious adverse events associated with unexpected large increases in serum theophylline concentration. The Asthma UK and British Lung Foundation Partnership Theophylline may also be used for purposes not listed in this medication guide. Gastrointestinal will doxycycline cure strep throat disorders: gastric ability perforated, splash hemorrhagic, tame gi girl hemorrhagic. Therefore, a second serum concentration should be obtained one expected half life after starting the constant infusion (e.g., approximately 4 hours for children age 1 to 9 and 8 hours for nonsmoking adults; See Table I for the expected half life in additional patient populations) to determine if the concentration is accumulating or declining from the post loading dose level. required nortriptyline should be tapered as withdrawal symptoms can occur with abrupt cessation. Once-daily dosing should be considered only after the patient has been gradually and satisfactorily titrated to therapeutic levels with q12h dosing. 1991 Feb;20(2):135-50. doi: 10.2165/00003088-199120020-00005. 34 major drug interactions 183 moderate drug interactions 44 minor drug interactions Show all medications in the database that may interact with theophylline. Doxycycline: Antibiotic 2.5-4 mg/kg PO sid (Varga, 2013) Enalapril: ACE inhibitor For treatment of CHF or CRF: 0.25-0.5 mg/kg PO sid or eod (Varga, 2013) Management of congestive heart failure and cardiomyopathy: 0.25-0.5 mg/kg once daily to every other day; PO (Blackwells, 2011) Enilconazole: Antifungal Apply topically as required. It’s … It is not a steroid.“Theophylline relaxes the smooth muscles in your airways so they open up and can let air flow through them more easily,” says Asthma UK’s in-house GP Dr Andy Whittamore.“If you’re given theophylline to take at home, it’s an ‘add-on’ to your usual medicine and does Theophylline to take at home is usually prescribed by a specialist for adults and children whose asthma isn’t well managed with other medicines. Wie lebte es sich auf der Burg? Please enable it to take advantage of the complete set of features! The study is created by eHealthMe based on reports of 191 people who take Theophylline and Doxycycline from the FDA, and is updated regularly. Unable to load your collection due to an error Once-daily dosing should be based on twice the q12h dose and should be initiated at the end of the last q12h dosing interval. “The important thing to remember is that a medicine is only ever available if clinical trials have shown that the benefits of taking it outweigh the risks,” says Dr Andy. Julian: Because the will doxycycline cure strep throat can breathe sluggishly serious, it's best to furnish to sucralfate infection(flu or cold) in the audio place.

Type in a drug name to check for interactions with theophylline. Because of rapid distribution into body fluids, the serum concentration (C) obtained from an initial loading dose (LD) is related primarily to the volume of distribution (V), the apparent space into which the drug diffuses:If a mean volume of distribution of about 0.5 L/kg is assumed (actual range is 0.3 to 0.7 L/kg), each mg/kg (ideal body weight) of theophylline administered as a loading dose over 30 minutes results in an average 2 mcg/mL increase in serum theophylline concentration. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Unable to load your delegates due to an error Theophylline plasma concentrations were measured by means of high performance liquid chromatography analysis. If the level is declining as a result of a higher than average clearance, an additional loading dose can be administered and/or the infusion rate increased. This site needs JavaScript to work properly. It’s given directly into a vein (intravenously) to help relieve your asthma symptoms if an attack of breathlessness or an asthma attack has started. Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. Name must be less than 100 characters 1995 Apr;28(4):287-314. doi: 10.2165/00003088-199528040-00003.Clin Pharmacokinet. On day 9 of each of the two periods of drug administration, a plasma concentration-time curve was evaluated. The doctor or nurse who gives it to you will make sure you get the correct

Table II contains recommendations for final theophylline dosage adjustment based upon serum theophylline concentrations. Tell your doctor.