Imuran dosage for lupus zyban



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I'm exhausted from being so dehydrated and malnourished.

I might add that my current bleeding issues with pre-menopause and abnormal cells in my uterus I truly believe where due to long term use of this drug. Diseases & Conditions

My dr thought I had a virus but told me to stop taking the imuran. I can't handle it anymore.” Home; About; Posts; Members; Azathioprine dose . I had blood work and all my values are normal now which was not the case before. Helps on lower dosage but not as well.” Called rheumy & I was taken off med. Possible side effects 5. Usual Pediatric Dose for Systemic Lupus Erythematosus Several guidelines on this subject have been published.

Select one or more newsletters to continue. I can now walk thanks to this. They belong to a group of medicines called immunosuppressives.

1107742-overview Just average basically, all the time. I could tell a big difference in how I felt. Azathioprine comes in two forms: an oral tablet and an injectable solution. Within a little over 24 hours, the headache started going away, the urine went back to normal color and my body was feeling better.” Before taking Imuran I was on methotrexate and Lyrica which I had EVERY SIDE EFFECT to. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. 1209403-overview Azathioprine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. imuran (azathioprine) is a medication originally used to prevent rejection of transplanted organs.

3-5 mg/kg/day IV/PO initially on day of transplant; 1 to 3 days prior to transplantation also reported (rare) 1 mg/kg/day IV/PO initially in single daily dose or divided q12hr; after 6-8 weeks, increase by 0.5 mg/kg/day every 4 weeks; not to exceed 2.5 mg/kg/day Maintenance: Reduce daily dose by 0.5 mg/kg every 4 weeks until lowest effective dosage is reachedInduction and maintenance therapy for lupus nephritis (2012 American College of Rheumatology guidelines)2 mg/kg/day PO with or without low-dose corticosteroids 1-2 mg/kg PO once daily to maximum daily dose of 150 mg for at least 3-6 months before typical response is observed1 mg/kg/day IV/PO initially in single daily dose or divided q12hr; may be increased by 0.5 mg/kg/day after 6-8 weeks, then by 0.5 mg/kg/day every 4 weeks; not to exceed 2.5 mg/kg/day Maintenance: Reduce daily dose by 0.5 mg/kg every 4 weeks until lowest effective dosage is reached3-5 mg/kg/day IV/PO initially on day of transplant or 3 days before transplant (rare) Induction and maintenance therapy for lupus nephritis (2012 American College of Rheumatology guidelines)>12 years: 2 mg/kg/day PO with or without low-dose corticosteroidsSweet syndrome (acute febrile neutrophilic dermatosis)Chronic immunosuppression with this purine antimetabolite increases neoplasia risk, mutagenic risk, and hematologic toxicitiesReported malignancies include posttransplant lymphoma and hepatosplenic T-cell lymphoma (HSTCL) in patients with inflammatory bowel diseasePrescribing physicians should be familiar with mutagenic potential and with possible hematologic toxicitiesRheumatoid arthritis: Patients previously treated with alkylating agentsIncreased risk of infection and hepatotoxicity; monitor liver function periodically; hepatic sinudoidal obstruction syndrome reported; discontinue therapy if suspectedCases of JC virus-associated infection resulting in progressive multifocal leukoencephalopathy (PML), sometimes fatal, reported in patients treated with immunosuppressants, including azathioprineSevere leukopenia, thrombocytopenia, anemias including macrocytic anemia, and/or pancytopenia may occur; severe bone marrow suppression may also occur; patients with or nucleotide diphosphatase (NUDT15) deficiency may be at an increased risk of myelotoxicity if patient receiving conventional doses of drug; delayed hematologic suppression may occur; prompt reduction in dosage or temporary withdrawal of drug may be necessary if there is rapid fall in or persistently low leukocyte count, or other evidence of bone marrow depression; leukopenia does not correlate with therapeutic effect; therefore dose should not be increased intentionally to lower white blood cell countIn patients with severe myelosuppression, consider evaluation for TPMT and NUDT15 deficiency; consider alternative therapy in patients with homozygous TPMT or NUDT15 deficiency and reduced dosages in patients with heterozygous deficiencyPatients receiving immunosuppressants, are at increased risk for bacterial, viral, fungal,protozoal, and opportunistic infections, including reactivation of latent infections; these infections may lead to serious, including fatal outcomesFrequency of gastrointestinal adverse effects (nausea and vomiting) may decrease with dividing dose or administering after mealsLactation: Drug excreted at low levels in breast milk; use not recommendedA: Generally acceptable.
When I see my rheumatologist in a week, I'm begging him to try anything else but Imuran. “I'm a women age 39. I also take predisone.” I have since learned (from a doctor at the John Hopkins Lupus Center) that there is a test to determine if you will tolerate Imuran.

However, I wish I had known that a test was available to determine if a patient will tolerate Imuran as this would have been extremely helpful and I could have avoided a very serious allergic reaction to Imuran.” The optimum duration of maintenance IMURAN has not been determined. I have neurological involvement and before this medicine my right foot was paralyzed.