Topical acyclovir applied to small areas of the mother's body away from the breast should pose no risk to the infant. 1987;69 (3 pt 2):468-71. Check with your doctor immediately if any of the following side effects … [PubMedTaddio A, Klein J, Koren G. Acyclovir excretion in human breast milk.

We shall be discussing both the side-effects … Acyclovir Levels and Effects while Breastfeeding Summary of Use during Lactation Even with the highest maternal dosages, the dosage of acyclovir in milk is only about 1% of a typical infant dosage and would not be expected to cause any adverse effects in breastfed infants. [PubMedMeyer LJ, de Miranda P, Sheth N et al. Along with its needed effects, a medicine may cause some unwanted effects. Consult your doctor before taking Valtrex if pregnant or breastfeeding. Three milk acyclovir levels on days 5 and 6 of therapy ranged from 4.2 to 5.8 mg/L, with the highest level 9.4 hours after the previous dose. Unexpected accumulation of acyclovir in breast milk with estimation of infant exposure. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects.

Regul Toxicol Pharmacol. Maternal Levels.Five mothers who were nursing neonates were given valacyclovir 500 mg orally every 12 hours for 5 days.

Acyclovir in human breast milk. For acyclovir, the following should be considered:Tell your doctor if you have ever had any unusual or allergic reaction to acyclovir or any other medicines. You may report side effects to the FDA at 1-800-FDA-1088.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Many people have no side effects at all, or only minor ones. Because the infant receives breastmilk doses orally and acyclovir is only about 20% orally bioavailable,[5] the systemic dosage that the nursing infant receives is 1% or less of a typical infant dosage.The mother of a 4-month-old infant noticed no adverse effects in her breastfed infant while she was taking an acyclovir dosage of 800 mg orally 5 times daily. [6] Using the level 6 hours after the last dose, a fully breastfed infant would receive a daily dosage of 1.1 mg/kg with this maternal dosage regimen.Acyclovir is given to neonates in intravenous dosages of 20 to 30 mg/kg daily. Acyclovir is an antiviral drug. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking. It slows the growth and spread of the herpes virus so that the body can fight off the infection.

Dosages received in breastmilk with high maternal doses are only about 3 to 5% of this dose. Obstet Gynecol. Select one or more newsletters to continue. J Am Acad Dermatol.

[4] A mother nursing her 7-month-old infant took acyclovir 800 mg orally 5 times a day.

The peak level was 7.3 mg/L and the drug was detectable in milk for up to 88 hours after the last dose. Even with the highest maternal dosages, the dosage of acyclovir in milk is only about 1% of a typical infant dosage and would not be expected to cause any adverse effects in breastfed infants. [PubMedBork K, Benes P. Concentration and kinetic studies of intravenous acyclovir in serum and breast milk of a patient with eczema herpeticum. For non-prescription products, read the label or package ingredients carefully.Appropriate studies have not been performed on the relationship of age to the effects of acyclovir ophthalmic ointment in children younger than 2 years of age. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. 1994;28:585-7. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.The dose of acyclovir will be different for different patients. Available for Android and iOS devices. This is a decision you and your doctor will make. [PubMedFrenkel LM, Brown ZA, Bryson YJ et al. The authors estimated that a fully breastfed infant would receive a daily dosage of 0.73 mg/kg of acyclovir at this maternal dosage or about 1% of the maternal weight-adjusted dosage. Milk samples were taken every 6 hours after the last dose. Side Effects of Taking Acyclovir Acyclovir is a safe drug; however, it may sometimes cause some mild to severe side-effects in people.