–Tinea versicolor: Brown or white macules/patches and thin plaques involving predominantly the front of the chest, neck, and back.

Oral erythromycin isn't the first, nor necessarily the best, treatment choice for acne. The American Academy of Dermatology recommends that clindamycin always be used with other acne medications to reduce the risk of developing bacterial resistance to the antibiotic.

The frequency of a concomitant fungal component (especially in the setting of interdigital disease) and the known anti-inflammAtory properties, as well as the previously demonstrated efficacy of azole antifungals, make this class of treatment a comparable first-line therapy to clindamycin. Today we have newer antibiotics that are the more popular choice. Examples include: cyclosporine, cisapride (risk of arrhythmias), carbamazepine, digoxin, warfarin, ergot alkaloid, HMG CoA-reductase inhibitors.
Pediatric patients should be dosed at 30 to 50mg/kg/day, split into two doses, for 14 days. –Inverse psoriasis: Pink to red, often minimally scaling, potentially very pruritic, plaques involving the body folds. If you wish to read unlimited content, please log in or register below. )(In this study of 13 patients with erythrasma, red light (635nm) was employed to target the bacterial porphyrins as a means of eradicating the infection. Oneof three patients reported mild gastrointestinal discomfort.

In both the setting of extensive, progressive, or frequently recurrent disease, a workup for diabetes or an underlying debilitating disease is warranted. The guideline discusses various acne treatments including: This guideline does not examine the treatment of acne sequelae (e. g. scarring, post-inflammatory dyschromia). Your dermatologist will most likely prescribe a topical acne medication to use while you're taking oral erythromycin. All rights reserved. Colonization with Cutibacterium acnes does not differ significantly between patients with acne and healthy controls, with phylotype IA strains found predominantly in patients with acne, particularly in patients with erythromycin resistance, according to the results of a study conducted in France and published in the Journal of the European Academy of Dermatology and Venereology. Clayton, YM, Knight, AG. A single dose of clarithromycin 1gm demonstrated clearance of erythrasma within 2 weeks. Lesions often begin as pink or red (Figure 1) and over time develop a brown discoloration. Patients should be advised to allow their shoes to fully dry before wearing them. However, efficacy in interdigital erythrasma has yet to be demonstrated. Erythromycin is the treatment of choice for diffuse or extensive erythrasma, but considered second line for limited infection. Ⓒ 2020 About, Inc. (Dotdash) — All rights reservedCasey Gallagher, MD, is board-certified in dermatology. Ask the patient if he/she showered within 12 hours before the visit.

Erythromycin Topical Product () Concepts: Clinical Drug (T200) SnomedCT: 350155007: English: Topical erythromycin, Erythromycin, Topical, erythromycin topical, topical erythromycin, Erythromycin Topical Product, Topical form erythromycin (product), Topical form erythromycin, Topical erythromycin (product), Topical erythromycin (substance) –Clindamycin 2% solution or lotion applied twice a day for 1-2 weeks is highly effective in treating erythrasma. )(In a double blind, randomized, multicenter study, daily application of oxiconazole cream was effective is treating erythrasma. Biopsy and tissue cultures can aid in the diagnosis. )(In this 7-day comparative study, oral erythromycin was more effective than tetracycline in treating axillae and groin lesions (90% vs 70% respectively. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Santos-Juanes, J, Galache, C, Martinez-Cordero, A, Curto, JR, Carrasco, MP, Ribas, A. The authors recommend erythromycin 250mg orally 4 times daily for 14 days as the treatment of choice, with the recommendation for topical therapies in the setting of treatment failure or contraindication for systemic therapy. And, compared to these other options, erythromycin simply isn't the most effective antibiotic treatment for acne. Besides acne, erythromycin is used to treat a wide variety of conditions, from ear infections to To reduce the risk of recurrence, patients should be instructed to minimize bacterial colonization by using antibacterial washes or benzoyl peroxide gel/wash. They reported cultivatable treponema to be very susceptible to the action of erythromycin. –Tinea pedis: Scaling, macerated in the toe clefts; possible bullous lesions; positive KOH examination with hyphae –Allergic or irritant contact dermatitis: Erythematous, potentially vesiculated (in the acute form), potentially scaling and fissured plaques. Erythrasma is caused by Corynebacterium minutissimum, a gram positive, catalase positive aerobe that is considered part of the normal skin flora. Coccobacilli and filaments of Corynebacterium minutissimum in the stratum corneum (H&E, 60x) Holdiness, MR. “Management of cutaneous erythrasma”. Eichenfield LF, et al. Demonstrated similar efficacy to systemic erythromycin for axillary or groin erythrasma and superior efficacy to oral tetracycline. Bacterial culture is rarely warranted but can be accomplished in a modified tissue culture medium 199. Seville, RH, Somerville, A. The Licensed Content is the property of and copyrighted by DSM.