It is readily soluble in water and acids, but relatively insoluble in alkalis.Oxybutynin relaxes bladder smooth muscle.

Do not take this medicine in larger or smaller amounts or for longer than recommended.Take this medication with a full glass of water. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects).Antimuscarinic activity resides predominantly in the R-isomer. INDICATIONS. The extended-release oral tablet is available as a generic and a brand-name drug.

Blue scored tablets (5 mg) are engraved with DITROPAN on one side with 92 and 00, separated by a horizontal score, on the other side. Other drugs may interact with Ditropan XL, including prescription and over-the-counter medicines, vitamins, and herbal products. Pharmacist: Dispense in tight, light-resistant container as defined in the USP. The empirical formula of oxybutynin chloride is COxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. Select one or more newsletters to continue. Ditropan XL is available in generic form. Both enantiomers of oxybutynin are highly bound (>99%) to plasma proteins. The volume of distribution is 193 L after intravenous administration of 5 mg oxybutynin chloride. Brand name: Ditropan XL. Do not start a new medication without telling your doctor. Ditropan XL (oxybutynin) reduces muscle spasms of the bladder and urinary tract.Ditropan XL is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.Ditropan XL may also be used for purposes not listed in this medication guide.a blockage in your digestive tract (stomach or intestines); orBefore using Ditropan XL, tell your doctor if you havea nerve disorder that affects your heart rate, blood pressure, or digestion;gastroesophageal reflux disease (GERD) or heartburn; orAvoid becoming overheated or dehydrated during exercise and in hot weather. Available for Android and iOS devices. Be careful if you drive or do anything that requires you to be alert and able to see clearly.There are many other medicines that can interact with oxybutynin. ®-treated Adult Subjects in Five Double-blind, Controlled Clinical Trials of Ditropan XLGeneral Disorders and Administration Site ConditionsGeneral disorders and administration site conditions:General Disorders and Administration Site Conditions:Figure 1: Mean R-oxybutynin plasma concentrations following a single dose of Ditropan XL® Once Daily (n=19), All Available Data Normalized to an Equivalent of Ditropan XLFigure 2: Mean steady state (± SD) R-oxybutynin plasma concentrations following administration of 5 to 20 mg Ditropan XLSchizosaccharomyces pompholiciformis, Saccharomyces cerevisiaeFigure 3: Mean Change (±SD) in Urge Urinary Incontinence Episodes Per Week from Baseline (Study 1)Figure 4: Mean Change (±SD) in Urge Urinary Incontinence Episodes Per Week from Baseline (Study 2)Figure 5: Mean Change (±SD) in Urge Urinary Incontinence Episodes Per Week from Baseline (Study 3)We comply with the HONcode standard for trustworthy health information -

There are no adequate and well-controlled studies using Ditropan XLBased on animal data, oxybutynin is predicted to have a low probability of increasing the risk of adverse developmental effects above background risk.Reproduction studies with oxybutynin chloride in the mouse, rat, hamster, and rabbit showed no evidence of impaired fertility or harm to the animal fetus.It is not known whether oxybutynin is excreted in human milk. DITROPAN® (oxybutynin chloride) Tablets are supplied in bottles of 100 tablets (NDC 17314-9200-1). A metabolite, desethyloxybutynin, has pharmacological activity similar to that of oxybutynin in In patients with conditions characterized by involuntary bladder contractions, cystometric studies have demonstrated that oxybutynin increases bladder (vesical) capacity, diminishes the frequency of uninhibited contractions of the detrusor muscle, and delays the initial desire to void.The relative bioavailabilities of R- and S-oxybutynin from Ditropan XLSteady state oxybutynin plasma concentrations are achieved by Day 3 of repeated Ditropan XLThe rate and extent of absorption and metabolism of oxybutynin are similar under fed and fasted conditions.Oxybutynin is widely distributed in body tissues following systemic absorption. Overdose can lead to death.Ditreopan XL may cause blurred vision and may impair your thinking or reactions. 5 mg: Pale yellow, round, tablet with "5 XL" printed on one side with black ink.10 mg: Pink, round, tablet with "10 XL" printed on one side with black ink.Angioedema of the face, lips, tongue and/or larynx has been reported with oxybutynin. Ditropan XL ® (oxybutynin chloride) is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.. Ditropan XL ® is also indicated for the treatment of pediatric patients aged 6 years and older with symptoms of detrusor overactivity associated with a neurological condition (e.g., spina bifida). Downsides.

Generic Ditropan XL Availability. Do not use this medication without telling your doctor if you are breast-feeding a baby.Take Ditropan XL exactly as prescribed by your doctor. If involvement of the tongue, hypopharynx, or larynx occurs, oxybutynin should be promptly discontinued and appropriate therapy and/or measures necessary to ensure a patent airway should be promptly provided.Oxybutynin is associated with anticholinergic central nervous system (CNS) effects As with any other nondeformable material, caution should be used when administering Ditropan XLBecause clinical trials are conducted under widely varying conditions, the adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.The discontinuation rate due to adverse reactions was 4.4% with Ditropan XLThe following adverse reactions were reported by <1% of Ditropan XLThe following additional adverse reactions have been reported from worldwide postmarketing experience with Ditropan XLAdditional adverse events reported with some other oxybutynin chloride formulations include: cycloplegia, mydriasis, and suppression of lactation. You may report side effects to FDA at 1-800-FDA-1088.Taking this medicine with other drugs that make you sleepy can worsen these effects. Skip the missed dose if it is almost time for your next scheduled dose. Follow all directions on your prescription label. Common side effects of Ditropan XL include: dry mouth, ; drowsiness, headache DITROPAN XL ® (oxybutynin chloride) is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.. DITROPAN XL ® is also indicated for the treatment of pediatric patients aged 6 years and older with symptoms of detrusor overactivity associated with a neurological condition (e.g., spina bifida). Important Information