I also think it has helped my musculoskeletal symptoms as well.My diagnosis is C-ANCA associated vasculitis, but my symptoms are more like PMR and giant cell arteritis; I do have the PR3 antibody at low titre.I see that a new drug has been approved by USA FDA for giant cell arteritis called Actimmune (tocilizumab); it seems similar to Rituximab, and both approved for RA too which I do not seem to have.Anyway, it's reassuring to know I am not the only one with tinnitus associated with methotrexate.I am hoping to get an appt.with a neuro-ophalmologist At U. of Pennsylvania not far from where I live. It's getting rave reviews. In my (brief) experience, I have learned that the more stressed, anxious, upset or overwhelmed I am, the more unbearable the sound is. There are distraction techniques which help to reduce it's intrusion but it's forever there. My nutritionist, who also suffered from RA, experienced tinnitus from her DMARDs, as well. Who knows why us, we gave this and we eill find an answer. "Genetic knock out of TNF-A or pharmacologically blocking its expression prevented neuro-inflammation and ameliorated the behaviour associated with tinnitus in mice with noise-induced hearing loss. Over time, this therapy is said to reduce the loudness of your tinnitus, as it helps your brain adapt to become less sensitive to this frequency. I started taking methotrexate last November, and just shortly after, my tinnitus started.

It get so loud that I don't stand a chance to hear what people talk about. I have never experienced tinnitus until now.

As soon as I'm on a lower dose of Pred again the Tinnitus disappears. I have had RA for...bearly sleep night cos of pain...I know it is not a flu which goes away, but I still believe it...really helped me understand my RA more and to see I'm not alone.

I will give you an update as soon I get my order and take as directed. My rheumatologists also deny that this could be the result of the medicine, which to me is so infuriating! But I would think angiogram and cardiovasularlar study is a must b/c giant cell arteritis is a large vessel inflammation involving the chest and heart.Sorry to all of you suffering from these blood vessel inflammation diseases and effects on quality of our lives. God knows we all need themHi, I've had tinnitus for 10 or so years now. Your doctor will examine your ears, head and neck to look for possible causes of tinnitus. Tinnitus …

So I started lipreading classes and that has helped.

It is horrible and so debilitating. Just yesterday I called my sister and broke down and balled like a baby just wishing it would go away. And whilst the condition can be treated and improved, a cure has yet to be found. I don't suffer from it. Im afraid the only answer is that the more you simply ignore it the less effect it has and the less effect it has the more you tend to ignore it. Plz. He is published on Actimmune for giant cell arteritis; based on his article, I have not had some testing such as angiograms or vascular studies; this seems like a lapse to me.Would love to hear from anyone what testing they have had for giant cell arteritis; A biopsy can only confirm, but with a negative result , you can still have it. All I know is I'm believing in God to take this noise away for good, never to return. I truly do feel for you. Scientists from the University Of Arizona have been working to develop a cure for the extremely bothersome ear ringing condition known as tinnitus. Some individuals may believe that an external source is the origin of sound and look for it until they discover that it’s originating inside them. For her, the ringing went away after a full 6 months of stopping the meds, though she warns me that it could take up to 9. I got myself an electronic white noise machine which helped me become able to cope with the tinnitus and now i usually only notice it on bad days. It goes with the beat of my heart (so says the source on MES, and I've found it to be true -- slowing down when I'm in bed trying to go to sleep. After about 5-6 years being free from this horrible noise 3 days ago I got myself worked up due to my husband losing his job and somehow this monester showed it's ugly head and it's back with a vengence. For sufferers of tinnitus, there is no escaping the endless buzzing and whistling. Literally, I was disabled, RA doc said he doubted the mtrex.caused it gave me a script of percoset and sent me on my way. This began in September, about 2 weeks after weaning off of Prednisone (which I'd been on since late January). I don't know how, it's like another member said when she stopped the metho after 6 mths or so it went away. However it always lingered in the back of my brain but I had learned to mask it or something .I'm not sure. (pet hate: Hearing aids: like a walking aid, you're still bad at walking but you can get around better - NOT like glasses that correct vision. Your mileage may vary. Unfortunately there is no cure, the chances are its just as likely the stress you were going through with the onset of RA and yes the meds will have changed your system and up popped the dreaded tinnitus, it could be there tomorrow forever or go the next day and never come back. I'm so sorry you're experiencing this all again! share if you know about or have experience with this post. I can't tolerate methotrexate and it made me seriously ill, tinnitus was one of the many lousy side effects I got from itI began Methotrexate 4 weeks ago. There's more data.