According to the AHA’s analysis of clinical trials:However, some researchers believe that participants in statin trials have not been representative of the general population, so the results may underestimate the true prevalence of statin-related side effects.

Sakado, Japan—When statin-induced muscle pain and other musculoskeletal adverse events (MAEs) appear in some patients varies considerably within the drug class, a new study suggests. However, don't stop taking a statin without telling your doctor. Moreover, recent research indicates that they may benefit high risk individuals over age 75 as well.Taking a statin may give you some assurance that you're doing all you can to avoid heart attack and stroke, but you may also experience side effects. Your doctor should also make sure that other drugs you’re taking are not boosting the blood level of your statin. While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people who take them and may rarely cause liver damage.Statins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid).Having too much cholesterol in your blood increases your risk of heart attacks and strokes. Although there are no proven remedies for statin-related muscle pain, the following may help.Get health information and advice from the experts at Harvard Medical School.Don't fixate on your cholesterol, blood sugar, or blood pressure numbers. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.

By activating your account, you will create a login and password. For more than 20 years, cholesterol-lowering statin drugs have been a mainstay for preventing and treating heart disease. © 2020 The Regents of the University of California Statins may cause a dose-related rise in blood markers for liver damage in about 1 percent of people, but this alone does not indicate clinically significant liver injury.

Elevated levels of CPK, or creatine kinase, a muscle enzyme that when elevated, can cause muscle pain, mild inflammation, and muscle weakness.

They are routinely recommended for people who have cardiovascular disease and for many people ages 40 to 75 who don't have cardiovascular disease but have at least one risk factor (high blood pressure, high cholesterol, diabetes, or smoking) and a 7.5% or greater risk of a stroke or heart attack in the next decade. However, don't stop taking a statin without telling your doctor. As little as 15 minutes of moderate-intensity activity most days of the week can help lower your cardiovascular risk.

SAMS can vary in frequency and severity. The nocebo effect is the flip side of the placebo effect, in which positive expectations contribute to benefits. Don't stop taking your statin medication before talking to your doctor. If you still feel pain, try … You may feel this pain as a soreness, tiredness or weakness in your muscles. While blinded, participants in the statin and placebo arms reported similar rates of muscle symptoms. A common side effect of statin medications is muscle pain in major muscle groups. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.The increase generally occurs when blood sugar levels are already higher than normal and fall in the prediabetes or diabetes range when you begin taking a statin.Statins prevent heart attacks in people with diabetes, so the relevance of the mild increase in sugar values with statins observed in some people is unclear.