People are increased risk include people who: Combining more than one NSAID, such as Advil and Aleve, will not help relieve your pain faster than taking just one NSAID. NSAIDs also interact with other medications including angiotensin converting enzyme (ACE) inhibitors, angiotensin-II receptor blockers (ARBs), diuretics, clopidogrel, warfarin, dabigatran, and aspirin.When taking any NSAID, the following guidance is given:Use these dosage charts for infants and children under 12 years old:The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Both of these drugs work … Advil also contains sodium because the manufacturer claims that sodium ibuprofen is more soluble in water than standard ibuprofen. Aleve is a brand (trade) name for naproxen and ibuprofen is the drug name of a different NSAID (common brand names of ibuprofen include Advil and Motrin IB). Low-dose ibuprofen (such as Advil in dosages up to 1200mg per day) is considered an alternative to naproxen; however, higher dosages of ibuprofen (up to the recommended maximum of 2400mg/day) are associated with a higher risk of cardiovascular events. You can also increase your risk of certain side effects from taking too much of an NSAID or from taking them for too long.Both Advil and Aleve can cause similar side effects. You open the cabinet, hoping to find something to help with the pain and discomfort, but find yourself faced with three choices: Advil, Aleve and Tylenol. Tylenol, Advil and Aleve are common pain relievers on drugstore shelves. We comply with the HONcode standard for trustworthy health information - What are the differences to consider before taking? Naproxen and ibuprofen are both Aleve and Advil are called nonselective NSAIDs because they block COX-2 enzymes (involved in pain signalling and inflammation) and also COX-1 enzymes (associated with a protective effect on stomach lining). Naproxen (Aleve) and ibuprofen (Advil, Motrin) are two of the most popular medication choices for muscle aches, joint pain, and inflammation from conditions like osteoarthritis. All NSAIDs have been associated with kidney toxicity and allergic-type reactions. To reduce the risk of GI side effects, NSAIDS should only be taken at their lowest effective dose, for the shortest possible time. If you have bleeding problems, you may notice frequent bruises or nose bleeds or bleeding from wounds that is difficult to stop. People with digestive system problems such as peptic ulcer disease and ulcerative colitis are at increased risk.NSAIDs can reduce your blood’s ability to clot. Ibuprofen is used for in the making if Advil while Naproxen is used while making Aleve. This can cause fluid retention and changes in the amount and frequency you urinate. It is better suited for the treatment of acute pain and is the most appropriate NSAID for children. Select one or more newsletters to continue. Available for Android and iOS devices. Aleve is more likely than Advil to cause GI side effects because it is longer acting. If you are prescribed low-dose aspirin to reduce your risk of a heart attack or stroke, then talk to your doctor BEFORE taking NSAIDs, as these may negate the protective effects of aspirin.Another worrying side effect of some NSAIDs is an increased risk of cardiovascular events such as a heart attack. Ibuprofen (Advil, Motrin) and naproxen (Anaprox) are drugs used to relieve mild to moderate pain, fever, and inflammation. Aleve (at dosages up to 1000mg per day) does not appear to be associated with an increased risk of detrimental vascular events, and experts tend to prefer NSAIDs that contain naproxen for this reason. You may notice bloody or black, tarry stools. For injuries or inflammatory symptoms, either ibuprofen or napr… If you’re like most people, you probably have at least one or two over-the-counter pain relief medications in there. Doubling up on NSAIDs (for example taking Aleve and Advil at the same time) is unnecessary, and to be avoided as it increases the risk of both GI and cardiovascular side effects. Aleve is better suited for the treatment of chronic conditions. For every 200mg of naproxen, Aleve contains 20mg sodium.The active ingredient in Advil is ibuprofen. Healthline Media does not provide medical advice, diagnosis, or treatment. Both of these drugs work in the same way and do the same thing to relieve pain. Advil and Aleve reduce the amount of prostaglandins that your cells have to release. All rights reserved. Ever wonder which over-the-counter medicine to give a child experiencing muscle aches or pain from a mild injury?