Topical application route (Patch, Extended Release)NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. You may report side effects to FDA at 1-800-FDA-1088.Although the risk of serious side effects is low when diclofenac is applied to the skin, this medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.Stop using diclofenac and seek emergency medical attention if you have This is not a complete list of side effects and others may occur. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. If you experience stomach pain, stomach upset, or notice black, tarry stools, contact your doctor as soon as possible.

These events can occur at any time during use and without warning symptoms. These side effects may go away during treatment as your body adjusts to the medicine. Call your doctor for medical advice about side effects. O 03. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

If experienced, these tend to have a Less Severe expression. This medication is for use on the skin only. However, taking care of yourself as discussed below may reduce the risks.

© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). These were the only adverse reactions that occurred in >1% of treated patients with a greater frequency in the VOLTAREN GEL group (7%) than the placebo group (2%).Table 1 lists the types of application site reactions reported.

Understanding corticosteroid side effects. Diclofenac and steroids. Pennsaid (diclofenac sodium topical solution) is a non-steroidal anti-inflammatory drug used to treat signs and symptoms of osteoarthritis of the knee(s).Common side effects of Pennsaid include: skin irritation (e.g., dryness, redness, stinging, itching, scaling, hives, swelling), drowsiness, Actavis U.S. (Alpharma USPD), Owings Mills, MD. With long-term use, corticosteroids can result in any of the following side effects. Of these, 355 patients were treated for osteoarthritis of 1 knee and 228 were treated for osteoarthritis of both knees. Application site reactions, including application site dermatitis, were the most frequent reason for treatment discontinuation.In the open-label, long-term safety study, distribution of adverse reactions was similar to that in the placebo-controlled studies. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Get emergency help immediately if any of the following symptoms of overdose occur:Some side effects may occur that usually do not need medical attention.

Side effects of injected corticosteroids Injected corticosteroids can cause temporary side effects near the site of the injection, including skin thinning, loss of color in the skin, and intense pain — also known as post-injection flare. Cerner Multum, Inc. "Australian Product Information." Solaraze (diclofenac topical)" SkyePharma, San Diego, CA. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events.Along with its needed effects, diclofenac topical may cause some unwanted effects.

Additionally, 583 patients were exposed to VOLTAREN GEL in an uncontrolled, open-label, long-term safety trial in osteoarthritis of the knee.

Common side effects. Application site dermatitis was the most frequent type of application site reaction and was reported by 4% of patients treated with VOLTAREN GEL, compared to 1% of placebo patients.In the placebo-controlled trials, the discontinuation rate due to adverse reactions was 5% for patients treated with VOLTAREN GEL, and 3% for patients in the placebo group.

More common Abdominal or stomach bloating, burning, cramping, or pain belching bloody or black, tarry stools cloudy urine constipation decrease in urine output or decrease in urine-concentrating ability diarrhea dizziness feeling of indigestion headache increased bleeding … This medication may increase the risk of bleeding when used with other drugs that also may cause bleeding. Drug information provided by: IBM Micromedex. All rights reserved. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment.