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Indicated for hypertension, to lower blood pressureLowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions5 mg/day PO initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day maintenance: 5-10 mg/dayTreatment of chronic stable angina, vasospastic angina (Prinzmetal or variant angina), and angiographically documented CAD in patients without heart failure or EF <40%5-10 mg/day PO initially; maintenance: 10 mg/day POStart dosing at low end of dosing range; elderly patients have greater frequency of decreased renal, hepatic or cardiac function2.5-5 mg/day PO initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day PO; maintenance: 5-10 mg/day POTreatment of chronic stable angina, vasospastic angina (Prinzmetal or variant angina), and angiographically documented CAD in patients without heart failure or EF <40%2.5-10 mg/day PO initially; maintenance: 10 mg/day POCardiovascular: Arrhythmia (eg, ventricular tachycardia, atrial fibrillation), bradycardia, chest pain, peripheral ischemia, syncope, tachycardia, vasculitisCentral and peripheral nervous system: Hypoesthesia, neuropathy peripheral, paresthesia, tremor, vertigoGastrointestinal: Anorexia, constipation, dysphagia, diarrhea, flatulence, pancreatitis, vomiting, gingival hyperplasiaGeneral: Allergic reaction, asthenia, back pain, hot flushes, malaise, pain, rigors, weight gain, weight decreaseMusculoskeletal system: Arthralgia, arthrosis, muscle cramps, myalgiaPsychiatric: Sexual dysfunction (male and female), insomnia, nervousness, depression, abnormal dreams, anxiety, depersonalizationSkin and appendages: Angioedema, erythema multiforme, pruritus, rash, rash erythematous, rash maculopapularSpecial senses: Abnormal vision, conjunctivitis, diplopia, eye pain, tinnitusUrinary system: Micturition frequency, micturition disorder, nocturiaAutonomic nervous system: Dry mouth, sweating increasedPulmonary edema (higher incidence in heart failure patients)Jaundice and hepatic enzyme elevations (mostly consistent with cholestasis or hepatitis)Symptomatic hypotension is possible, particularly with severe aortic stenosis; owing to gradual onset of action, acute hypotension unlikelyWorsening of angina and acute myocardial infarction (MI) can develop after dose is started or increased, particularly with severe obstructive CADExtensively metabolized by the liver and plasma elimination half-life is 56 hr in patients with hepatic impairment; titrate slowly when treating patients with severe hepatic impairmentLimited available data based on postmarketing reports are insufficient to inform a drug-associated risk for major birth defects and miscarriage during pregnancyLimited available data from a published clinical lactation study reports that amlodipine is present in human milk at an estimated median relative infant doseNo adverse effects of amlodipine on breastfed infant reportedThere is no available information on effects of amlodipine on milk productionA: Generally acceptable. • drugs for high blood pressure and heart trouble. 2010

This website also contains material copyrighted by 3rd parties. Individual plans may vary Lowering blood pressure may lower your risk of a stroke or heart attack. The magnitude of this interaction may be increased in patients who are also receiving cyclosporine. *Primarily to albumin. informational and educational purposes only.

2184611-overview Amlodipine is used to treat chest pain and other conditions caused by coronary artery disease.. Amlodipine is also used to treat high blood pressure (hypertension). All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. {12}6 {12}5 ‡ A primary metabolite for acetohexamide, hydroxyhexamide, accounts for 47 to 60% of dose and is 2.5 times more potent than its parent. If you log out, you will be required to enter your username and password the next time you visit. encoded search term (amlodipine (Norvasc)) and amlodipine (Norvasc) Coronary Sinus Stent May Aid Refractory Angina: Phase 2 TrialSimilar Clinical Outcomes With ARB, CCB for HTN in DiabeticsVitamin D and Risk of All-cause and Cause-specific MortalitySurgery for Reflex Sympathetic Dystrophy (Complex Regional Pain Syndrome Type 1)Share cases and questions with Physicians on Medscape consult.