You should not eat or drink grapefruit-containing products if you take medications classified as calcium-channel blockers to treat hypertension, Mayo Clinic advises. Grapefruit has vitamin C and potassium—nutrients your body needs to work properly.But it isn’t good for you when it affects the way your medicines work, especially if you have high blood pressure or arrhythmia (irregular or abnormal heart beat).This food and drug interaction can be a concern, says Shiew Mei Huang, PhD, of the U.S. Food and Drug Administration. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.

To understand why grapefruit does not interact with hydrochlorothiazide, you need to understand how this medication is eliminated from the body 3.Hydrochlorothiazide binds to different proteins in your blood, but does not undergo significant chemical changes 3.Hydrochlorthiazide is primarily excreted from your body in the urine, and approximately 95 … MgO.) Some people have a lot of enzymes and others just a little. All rights reserved. The FDA has required that some prescription and over-the-counter (OTC) drugs taken by mouth include warnings against drinking grapefruit juice or eating grapefruit while taking the drug, Huang says.Here are examples of some types of drugs that grapefruit juice can cause problems with (interact):Grapefruit juice does not affect all the drugs in the categories above. Hydrochlorothiazide grapefruit. So grapefruit juice may affect people differently even when they take the same drug.Although scientists have known for several decades that grapefruit juice can cause too much of certain drugs in the body, Huang says more recent studies have found that the juice has the opposite effect on a few other drugs.“Grapefruit juice can cause less fexofenadine to enter the blood,” decreasing how well the drug works, Huang says. It was the very first antihypertensive developed 60 years ago and is ...Thus eat the daily banana and glass of orange juice (and grapefruit, melons fish) for the potassium, DON'T restrict your salt and take a magnesium supplement (like 250 mg. Selected from data included with permission and copyrighted by First Databank, Inc. Hydrochlorothiazide is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids. We comply with the HONcode standard for trustworthy health information - Grapefruit juice can block the action of CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. He is currently a pathology resident at the University of Chicago. An official website of the United States government We study 194 people who take Grapefruit or Valsartan; hydrochlorothiazide. “When there is too much drug in the blood, you may have more side effects.”For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver and muscle damage that can lead to kidney failure.Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit is an excellent food for your health, but if you are on medication it would be prudent to inform you of a possible interaction. It is recommended that patients use the information presented as a part of a broader decision-making process.If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.© 2020 eHealthMe.com. Asked 10 Dec 2014 by Chautauqua2014 Updated 5 February 2019 Topics grapefruit, hydrochlorothiazide Can i eat grapefruit while taking methyprednisolone Can i eat grapefruit while taking cialis Connect by text or video with a U.S. board-certified doctor now — wait time is less than 1 minute! from the University of Chicago and a Ph.D. in pathology from the University of Chicago. Grapefruit juice can affect how well some medicines work, and it may cause dangerous side effects.Grapefruit juice and the actual grapefruit can be part of a healthy diet. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.

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