2002 If therapy is interrupted for several days, restart with 0.4 mg once daily.

If you log out, you will be required to enter your username and password the next time you visit. Prazosin hydrochloride, a quinazoline derivative, is the first of a new chemical class of antihypertensives. Um diesen Artikel zu kommentieren, melde Dich bitte an. All of these studies support the efficacy of prazosin either for treating nightmares and improving sleep or for reducing the severity of PTSD. The alpha blockers are relatively inexpensive and exert their effects quickly. Initial dose: 1 mg orally once a day at bedtime Maintenance dose: Initial dose may be increased slowly as needed and appropriate; usual recommended dose is 1 to 5 mg orally once a day Maximum dose: 20 mg/day Comments: If blood pressure response is substantially diminished 24 hours after dosing, an increased dose or use of a twice a day regimen can be considered. /viewarticle/937030 Diseases & Conditions 2002 Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. Maintenance: 6-15 mg/day divided 2 or 3 times daily; alternatively, 1-5 mg PO BID; may increase dose to 20 mg/day in divided doses; some patients may benefit from up to 40 mg/day in divided dosesMaintenance: 1 mg PO qHS initially; may increase dose to 2 mg qHS; adjust dose based on response and tolerability in 1-2 mg increments q7days; not to exceed 15 mg/day0.5-1 mg PO qDay (HS) or 0.5 mg PO BID; adjust dose based on response and tolerability up to 12 mg/day divided BID/TIDGive first dose and subsequent increases at bedtime to avoid syncopeRisk of syncope; has no relation to plasma prazosin concentration; if syncope occurs, place patient in the recumbent position and treat supportively as necessaryMay cause CNS depression, which may impair physical or internal abilities; use caution when performing tasks that require mental alertnessMay impair ability to drive/perform hazardous tasks due to dizzinessCataract surgery - Linked to intraoperative floppy iris syndromeConcomitant administration with PDE-5 inhibitor (eg, sildenafil) can result in additive blood pressure-lowering effects and symptomatic hypotension; initiate PDE-5 inhibitor therapy at lowest doseFirst dose effect may occur, causing a sudden and drastic fall in blood pressure after administration of the first dose.Prolonged erections and priapism reported with alpha-1 blockers including prazosin in post marketing experience; if erection persists > 4 hours, seek immediate medical assistanceMay cause significant orthostatic hypotension and syncope with sudden loss of consciousness, especially 30-90 min of first dose; may also occur if therapy interrupted for a few days, if dosage rapidly increased or if another antihypertensive drug, like a beta-blocker or vasodilator, or a phosphodiesterase 5 inhibitor is introducedProstatic carcinoma should be ruled out before initiating therapyA: Generally acceptable. Prazosin is also used to treat benign prostatic hyperplasia (BPH, noncancerous enlargement of the prostate), congestive heart failure, pheochromocytoma (adrenal gland tumor), sleep problems associated with post-traumatic stress disorder (PTSD; an anxiety disorder in people who experience or witness a traumatic, life-threatening event), and Raynaud's disease (condition where … Medizin-Lexikon. Your blood pressure should be checked regularly to determine your response to prazosin.Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking prazosin.Do not let anyone else take your medication. informational and educational purposes only. Fachgebiete : Arzneimittel. Prazosin dosing information.
We comply with the HONcode standard for trustworthy health information - It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine and its structural formula is:C 19H 21N 5O 4•HCl M.W. The recommended starting dose for treating BPH is 1 mg daily.

Dosage adjustment in renal impairment: Clcr >/= 10 mL/minute: No adjustment needed In 32 patients with benign prostatic hyperplasia (BPH) serum levels of zinc and magnesium were studied before and after prazosin therapy with (Minipress-Pfizer), 4 mg daily. Store it at room temperature and away from excess heat and moisture (not in the bathroom).It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. In 32 patients with benign prostatic hyperplasia (BPH) serum levels of zinc and magnesium were studied before and after prazosin therapy with (Minipress-Pfizer), 4 mg daily. 2002 Diseases & Conditions Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Food slows absorption and may decrease side effects. Only prazosin and terazosin are available in Australia, but doxazosin2and tamsulosin are being studied. Prazosin is the most commonly used alpha blocker. Controlled studies in pregnant women show no evidence of fetal risk.Alpha-1 blocker inhibits postsynaptic alpha-adrenergic receptors, causing arterial and venous dilation and a subsequent decrease in blood pressureAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. Controlled studies in pregnant women show no evidence of fetal risk.Alpha-1 blocker inhibits postsynaptic alpha-adrenergic receptors, causing arterial and venous dilation and a subsequent decrease in blood pressureAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans.