This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.© 2005-2020 Healthline Media a Red Ventures Company. Follow applicable special handling and disposal procedures [Swallow Hydroxyurea capsule whole. Advise protection from sun exposure and monitor for the development of secondary malignancies.Based on the mechanism of action and findings in animals, Hydroxyurea can cause fetal harm when administered to a pregnant woman.
The empirical formula is CHThe precise mechanism by which Hydroxyurea produces its antineoplastic effects cannot, at present, be described.
Wash your hands before and after handling the capsules or the bottle.Your doctor will monitor your blood cells. They will check either the number of cancer cells in your body or the shape of your red blood cells. Discontinue Hydroxyurea and manage with corticosteroids [Interference with Uric Acid, Urea, or Lactic Acid Assays is possible, rendering falsely elevated results of these in patients treated with Hydroxyurea The following clinically significant adverse reactions are described in detail in other labeling sections:The following adverse reactions have been identified during post-approval use of Hydroxyurea capsules.
Some drugs may have another patient information leaflet. Healthline Media does not provide medical advice, diagnosis, or treatment. Avoid exposure to crushed or opened capsules.
If contact with crushed or opened capsules occurs on the eye(s), the affected area should be flushed thoroughly with water or isotonic eyewash designated for that purpose for at least 15 minutes. Thrombocytopenia and anemia occur less often and are seldom seen without a preceding leukopenia.
Your doctor will write the number of refills authorized on your prescription. This makes it less likely for Hydroxyurea oral capsule can cause dizziness and drowsiness during the first few hours after you take it. Healthline Media does not provide medical advice, diagnosis, or treatment. Hydroxyurea will not …
You take both forms by mouth. Portions of this document last updated: Feb. 01, 2020Copyright © 2020 IBM Watson Health. The morphologic change resembles pernicious anemia, but is not related to vitamin BInterstitial lung disease including pulmonary fibrosis, lung infiltration, pneumonitis, and alveolitis/allergic alveolitis (including fatal cases) have been reported in patients treated for myeloproliferative neoplasm. Do NOT open, break, or chew capsule because Hydroxyurea is a cytotoxic drug.Prophylactic administration of folic acid is recommended [Monitor blood counts at least once a week during Hydroxyurea therapy. It prevents cancer cells from growing.
A class of drugs is a group of medications that work in a similar way. Zyvox is an oxazolidinone antibiotic that fights bacteria in the body. Almost all patients receiving an adequate course of combined Hydroxyurea and irradiation therapy will demonstrate concurrent leukopenia. Hydroxyurea causes the transformation of rodent embryo cells to a tumorigenic phenotype. Avoid exposure to sunlight or tanning beds. Using this medicine while you are pregnant can harm your unborn baby. Hydroxyurea is a prescription drug. The cap is opaque green, and the body is opaque light pink.
All rights reserved. Zyvox is an oxazolidinone antibiotic that fights bacteria in the body.
Keep these considerations in mind if your doctor prescribes hydroxyurea for you.A prescription for this medication is refillable. Select one or more newsletters to continue. Some side effects of hydroxyurea may occur that usually do not need medical attention. Mean peak plasma concentrations and AUCs increase more than proportionally with increase of dose.There are no data on the effect of food on the absorption of Hydroxyurea.Hydroxyurea distributes throughout the body with a volume of distribution approximating total body water.Hydroxyurea concentrates in leukocytes and erythrocytes.Up to 60% of an oral dose undergoes conversion through saturable hepatic metabolism and a minor pathway of degradation by urease found in intestinal bacteria.In patients with sickle cell anemia, the mean cumulative urinary recovery of Hydroxyurea was about 40% of the administered dose.The effect of renal impairment on the pharmacokinetics of Hydroxyurea was assessed in adult patients with sickle cell disease and renal impairment. This can be harmful or prevent the drug from working well.To help avoid interactions, your doctor should manage all of your medications carefully.
It is also used to increase fetal hemoglobin concentration, thus reducing the frequency of severe crisis and reducing the necessity for blood transfusions in patients with sickle cell anemia. Do not open Hydroxyurea capsules. This hypothesis explains why, under certain conditions, Hydroxyurea may induce teratogenic effects.Three mechanisms of action have been postulated for the increased effectiveness of concomitant use of Hydroxyurea therapy with irradiation on squamous cell (epidermoid) carcinomas of the head and neck. You may report side effects to FDA at 1-800-FDA-1088.Some medicines can increase your risk of serious side effects while taking hydroxyurea. If the capsule is opened or broken, do not touch the contents.