Ribavirin is an antiviral medication. The primary toxicity is Along with its needed effects, ribavirin may cause some unwanted effects. eCollection 2013 Nov. Throwing Up Acetazolamide inhibits cerebrospinal fluid production, and its effects are augmented by furosemide, suggesting a role for this combination in infants with ventricular dilatation resulting from severe periventricular hemorrhage. Falsely low hemoglobin A1c levels may be due to ribavirin-induced hemolysis decreasing the number of circulating glycosylated hemoglobin molecules.Psychiatric side effects associated with oral ribavirin in combination with peginterferon alfa-2a, peginterferon alfa-2b, or interferon alfa-2b have included irritability/anxiety/nervousness/emotional lability (up to 47%), Endocrine side effects associated with oral ribavirin in combination with peginterferon alfa-2a, peginterferon alfa-2b, or interferon alfa-2b have included hypothyroidism (up to 5%).Other side effects frequently associated with ribavirin tablets in combination with peginterferon alfa-2a have included Hepatic side effects have included hepatic dysfunction, fatty liver, and cholangitis in less than 1% of patients treated with peginterferon alfa-2a alone or in combination with ribavirin tablets. Not Feeling Well 6. Myositis has been reported in less than 1% of patients treated with peginterferon alfa-2a alone or in combination with ribavirin tablets.

"Product Information. Damage to contact lenses after prolonged close exposure to aerosolized ribavirin has also been reported.Most signs and symptoms reported in exposed health care workers resolved within minutes to hours of stopping close exposure to aerosolized ribavirin.Gastrointestinal side effects associated with oral ribavirin in combination with peginterferon alfa-2a, peginterferon alfa-2b, or interferon alfa-2b have included nausea (up to 47%), Musculoskeletal side effects associated with oral ribavirin in combination with peginterferon alfa-2a, peginterferon alfa-2b, or interferon alfa-2b have included myalgia (up to 64%), arthralgia (up to 34%), musculoskeletal pain (up to 28%), and back pain (5%). Ribavirin monotherapy is ineffective for treatment of chronic hepatitis C virus infection. Don’t take ribavirin with a high-fat meal. Am J Gastroenterol 94 (1999): 1686-813.

Roche Laboratories, Nutley, NJ. Please enable it to take advantage of the complete set of features! In a preliminary trial, supplementing with EPA partially prevented the decline in hemoglobin levels in patients with hepatitis C who were being treated with the combination of ribavirin and pegylated interferon alpha-2b. It can also cause other side effects.Ribavirin is used with peginterferon alfa. Pediatr Infect Dis J 9 (1990): 209-117. Wiley

An interaction is when a substance changes the way a drug works.

Unable to load your delegates due to an error Effects of ribavirin dose reduction vs erythropoietin for boceprevir-related anemia in patients with chronic hepatitis C virus genotype 1 infection--a randomized trial. Our website services, content, and products are for informational purposes only. Robertson M "Artificially low HbA1c associated with treatment with ribavirin." Simon-Talero M, Buti M, Esteban R "Severe anaemia related to oseltamivir during treatment of chronic hepatitis C: a new drug interaction?" Dove LM, Rosen RC, Ramcharran D, et al. Rodriguez WJ, Parrott RH "Ribavirin aerosol treatment of serious respiratory syncytial virus infection in infants." If they’re more severe or don’t go away, talk to your doctor or pharmacist.Call your doctor right away if you have serious side effects. All rights reserved. Virazole (ribavirin)."

e5. Janai HK, Marks MI, Zaleska M, Stutman HR "Ribavirin: adverse drug reactions, 1986 to 1988." doi: 10.1111/j.1440-1746.2008.05398.x. Edelson PJ "Reactions to ribavirin." Arch Dis Child 61 (1986): 593-722. Background and aim: Current practice guidelines recommend that individuals chronically infected with the hepatitis C virus (HCV) be treated with pegylated interferon plus ribavirin. This can happen if either the mother or father uses ribavirin during conception, or if the mother takes the drug during pregnancy.You and your doctor may need to decide if you’ll take ribavirin or breastfeed.All possible dosages and forms may not be included here. Symptoms can include:If you develop these symptoms, call 911 or go to the nearest emergency room. Antunes I, Azevedo F, MesquitaGuimaraes J, Resende C, Fernandes N, Macedo G "Grover's disease secondary to ribavirin." Expert Review Panel" 4. Taking ribavirin with interferons (alfa) might increase the risk for side effects, including low red blood cells (anemia), due to ribavirin treatment. 2004 Jul 29;351(5):438-50. doi: 10.1056/NEJMoa040842.Iacob S, Gheorghe L, Hrehoret D, Becheanu G, Herlea V, Popescu I.N Engl J Med. "Product Information.