In June 2004, Health Canada issued a In 2017, Health Canada decided to review all available evidence related to the effectiveness of the white blood cell monitoring measures currently in place for clozapine.The analysis that contributed to this safety review included scientific and medical literature, Canadian and international information, and what is known about the use of clozapine both in Canada and internationally. 100 mg clozapine oral tablet. Store the dissolving tablets in their Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Do not take two doses at one time.If you miss taking Clozaril for more than 2 days in a row, call your doctor before you start taking it again.Get your prescription refilled before you run out of medicine completely.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include drowsiness, confusion, fast heartbeats, feeling light-headed, weak or shallow breathing, Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.Further doses may be delayed until your infection clears up.High doses or long-term use of Clozaril can cause a serious movement disorder that may not be reversible. Publicly Funded Drug Programs Special Drug Programs. The longer you use Clozaril, the more likely you are to develop this disorder, especially if you are a woman or an older adult.Clozapine can increase your risk of seizure, especially at high doses. Before using clozapine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (This drug may make you dizzy or drowsy or blur your Tell your doctor if you are a descendent of Ashkenazi Jews because you may be at a higher risk for a drop in your white Liquid products or dissolving tablets may contain sugar and/or aspartame. Health Canada has advised health care providers prescribing and/or dispensing CLOZARIL® to assess Do not double the dose to catch up.Store at room temperature away from light and moisture. Many drugs can interact with clozapine. Learn More. Using Clozaril with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. HCP Type: Select Your HCP Type . Take your next dose at the regular time.

Follow your doctor's dosing instructions very carefully.Your doctor may recommend you use a laxative while taking Clozaril. Novartis in Canada responds to COVID-19 with commitments in key areas. Certify in the Clozapine REMS Program If you need to prescribe clozapine but are not yet certified in the Clozapine REMS Program, go immediately to clozapinerems.com.Once a prescriber is certified, his/her prescriber designees must also enroll online. Publications.

Avoid any activity that could be dangerous if you have a seizure or lose consciousness.uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);Untreated constipation may lead to serious bowel complications, hospitalization, or death. Weekly highlights from Skynews magazine.

License: Please select your profession. If it becomes necessary to stop this medication, the dose should be reduced gradually to prevent withdrawal effects. The risk of suicide in the general population is about 1%. However, if it has been more than 2 hours, skip the missed dose and go back to your regular dosing schedule. This is not a complete list of side effects and others may occur. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: facial/muscle Get medical help right away if you have any very serious side effects, including: severe dizziness, This medication may rarely cause a very serious condition called This is not a complete list of possible side effects.

Ask your pharmacist how to dispose of medications that are no longer needed or have expired.The side effects listed below are not experienced by everyone who takes this medication. Please try again. Here are their recommendations. Novartis in Canada responds to COVID-19 with commitments in key areas. About CLOZARIL. Do not stop taking this medication without talking to your doctor. To ensure that this does not happen, new information will be added to the Patient Registration Form. Effectiveness of measures to monitor low numbers of white blood cells (agranulocytosis) with clozapine use For Canadian Residents Only | Français Ready to learn more about Clozaril® ?

Your doctor may occasionally change your dose.Clozapine affects your immune system and can have long lasting effects on your body. Clozaril. down the sink or in the toilet) or in household garbage. If you miss doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose you were taking. Robotic Telescope. Effectiveness of measures to monitor low numbers of white blood cells (agranulocytosis) with clozapine useClozapine is a prescription drug authorized for sale in Canada to manage symptoms of schizophrenia when other drugs have not helped.Clozapine was developed in the 1960s.