Excess estrogen in the body can result in a higher risk of breast and uterine cancer. In study of elevated prolactin levels in transsexual women, of fifteen patients with persistently high prolactin levels, the patients were also reported to have developed enlarged pituitary glands. Estradiol levels increased from 12.1 to 16.4 pg/mL and 26.9 pg/mL with the low and high-dose patch, respectively.

You have room to go down in T and up in E, which an increase in E can do.

The following recommendations are based upon three sources, but the categorization of drugs into “recommended” and “less recommended” come from “Hormone Treatment in Transsexual People” (Asscheman and Gooren 1992). Whether it would help with sciatica, is unknown but certainly worth trying, if you are in a state where medical use is legal.

Many factors can affect what the results mean, such as age, sex, and health history.If the test results indicate low estradiol levels, they could signal one of the following:If the test results indicate high estradiol levels, they could signal one of the following:Pregnancy and a person’s menstrual cycle can affect the results in the following ways:In adolescents, high levels of estradiol could signal early puberty in girls and delayed puberty in boys.An estradiol test alone cannot diagnose a specific disease.

Well I have been on Hormones for about 2 1/2 years.

I'm just worried I guess.What is your Estrone levels? The liver function issues in the 1989 study were attributed to other causes, such as alcohol abuse and hepatitis B, and were mainly successfully treated, either with other medications or temporarily halting hormone treatment.In a German case study, bone loss was reversed in an MTF woman by adding 2 mg of oral estradiol valerate daily to the 100 mg of cyproterone daily she was already taking. The complications of hyperprolactinemia are limited, but can include blindness and hemorraging (Schenenberger & Knee 2001). Cis women can sport estrogen readings in the thousands when pregnant, and there are natural spikes in their hormonal cycles. This article compares recommendations from medical and non-medical sources, and explains conditions that could result from HRT, whether therapy is medically monitored or not. You should only be using one drug at the recommended dosage from each category.Note that mg is an abbreviation for milligrams, not to be confused with µg, the abbreviation for micrograms. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional.© 2004-2020 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Swallow? I’ve been doing my research. WhatsApp. He's never instructed me to do Sublingually or Buccal.

Nocturnal and spontaneous erections will usually stop in under a week. Buccal?

Male to Female Transition and Self Medicating Guide. Most of the worry about estradiol being too high is way overblown unless you already have prior risks such as obesity, diabetes, or genetic conditions that put you at elevated risk. Another study of transsexual women with elevated prolactin levels “suggest that the risk of inducing prolactinomas through cross-gender hormone treatment is likely to be small.” (Gooren et al 1985)Combined treatment with estrogen and cyproterone acetate [an androgen-blocker] is associated with transient elevation of liver enzymes (Asscheman, Gooren, & Eklund). An estradiol test alone cannot diagnose a specific disease.

Hyperkalemia, an often symptomless condition, can cause serious kidney problems, including renal failure, and heart problems, including difficult to cure cardiac rhythm disturbances.

In a German case study, bone loss was reversed in an MTF woman by adding 2 mg of oral estradiol valerate daily to the 100 mg of cyproterone daily she was already taking. He said it was looking good and it's increasing but I feel like they still aren't where they need to be.

Levels rise naturally during puberty and pregnancy, but the body also produces more estrogen in women who are overweight (fat cells can produce estrogen), or have high blood pressure or diabetes. In addition, high levels of estrogen are seen in women who are extremely overweight. Of those, four (19%) reported hormone regimens that were within the guidelines given by Asscheman and Gooren or Lawrence.Of those who were not within the guidelines, the differences ranged from the possibly ineffective to the potentially dangerous.

Five (25%) used a higher dose of anti-androgen than recommended, and four (19%) used a lower dose of anti-androgen than recommended.

High levels of estrogen can develop naturally, but too much estrogen can also result from taking certain medications. An estradiol test is a simple blood test to measure the amount of estradiol in a person’s blood. To avoid some confusion, the abbreviation for micrograms is not used in these tables.

There was no significant …

A case study comparing trans women who had been on estrogen for less than two years with those who’d been on it for longer found increased bone density in the women who’d been on estrogen longer (Reutrakul et al 1998).In a 1989 retrospective study, combined treatment with estrogen and cyproterone acetate [an androgen-blocker] was associated with increases in depressive mood changes (Asscheman, Gooren, & Eklund).

A microdose would be around 1mg daily.