- Participants will have imaging studies, such as chest x-rays and computed tomography scans, to study the tumors. This phase II trial studies the side effects and how well pembrolizumab in combination with gemcitabine, vinorelbine, and pegylated liposomal doxorubicin hydrochloride work in treating patients with Hodgkin lymphoma that has come back (relapsed) or does not respond to treatment (refractory). caesius, is the hydroxylated congener of daunorubicin.Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. 2. Background: Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. Patients ages 12 and older may be eligible for this study. Participants will continue treatment as long as they tolerate it and their KS improves.

Cancer information and support. - Participants will provide a complete medical history and have a full physical exam. Doxorubicin hydrochloride is subject to light degradation at 0.5 mg/mL, with considerable loss of bioactivity. A radioactive sugar molecule called fluorodeoxyglucose, or FDG, is used. - Participants who have Kaposi sarcoma will have photographs taken of their lesions. This study may or may not have a direct benefit for participants. The effect of doxorubicin and capecitabine on the quality of life measured by the SSQ is assessed.Johnson & Johnson Pharmaceutical Research & Development, L.L.C.Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USAKeywords provided by Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Most drugs used to treat it do not cross the blood-brain barrier. Peposertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. H . Drugs used in chemotherapy, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Xeloda Tablets 1195 INR Get Latest Price. It is believed that activated lymphocytes that may be found in patients disease might use more FDG because these cells burn more glucose fuel. The NovoTTF-100L(P) system is a portable device that uses electrical fields to stop the growth of tumor cells. This phase I trial studies the side effects and best dose of peposertib when given together with pegylated liposomal doxorubicin hydrochloride in treating patients with high or low grade ovarian cancer that has come back (recurrent). Combination therapy is not just limited to drug combinations. The study consists of a screening Phase (up to 14 days prior to treatment), treatment phase (up to 1 year), and post-treatment follow-up phase. Safety evaluations will consist of vital sign examination, physical examination, incidence and severity of adverse events, and laboratory tests findings and will be followed throughout the study.Pegylated liposomal doxorubicin 40 mg/m2 administered intravenously on Day 1 of each cycle. These cancers include Kaposi sarcoma and lymphoma. The clinical trials on this list are studying Pegylated Liposomal Doxorubicin Hydrochloride. You have reached the maximum number of saved studies (100).Please remove one or more studies before adding more.Jo Anne Zujewski, M.D., National Institutes of Health Clinical Center (CC)This phase II trial in patients with stage II and stage III breast cancer will test the feasibility of using cDNA microarray as a measure of a tumor's biological response to chemotherapeutic agents by characterizing the cDNA expression patterns in breast cancer before and after primary chemotherapy.
View more. The effect of doxorubicin and capecitabine on the quality of life measured by the EORTC QLQ-C30 is assessed.The SSQ consists of 4 items in which patients rate the degree to which they experienced an improvement or deterioration in their physical condition, emotional state, ability to enjoy their social life, and overall quality of life since there last QOL assessment.Each of the four items are rated on a 7 point Likert scale ranging from 0 = "very much worse" to 7 = "very much better".

Giving peposertib and pegylated liposomal doxorubicin hydrochloride may work better in treating patients with ovarian cancer compared to pegylated liposomal doxorubicin hydrochloride alone. View information & documentation regarding Doxorubicin hydrochloride, including CAS, MSDS & more. Interferon-alpha is given by injection into the skin. Capecitabine; Approved Uses * Breast cancer; Breast cancer metastatic; Chemotherapy; Colon cancer; Colon cancer metastatic Show more uses * Extracted from Drug Label. Valganciclovir can cause problems with bone marrow function, leading to low blood counts, sterility, and defects in a fetus. This is a Phase 1b / 2 study of AVB-S6-500 in combination with pegylated liposomal doxorubicin (PLD) or paclitaxel (Pac) in patients with platinum resistant recurrent ovarian cancer.