Il peut être prescrit pendant la grossesse.Ce médicament passe dans le lait maternel ; la poursuite de l'allaitement est possible, mais tout La solution injectable est obtenue en mélangeant la poudre avec le solvant fourni ou avec de l'eau pour préparation injectable. anaphylaxis) to another beta-lactam agent (e.g. Prolonged use may occasionally result in overgrowth of non-susceptible organisms.The occurrence at the treatment initiation of a feverish generalised erythema associated with pustula may be a symptom of acute generalised exanthemous pustulosis (AGEP) (see section 4.8). Satisfactory antibiotic concentrations are retained at 5 °C and at room temperature (25°C) in the recommended volumes of the following infusion fluids. However, close clinical monitoring should be performed during the combination and shortly after antibiotic treatment.Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3). En poursuivant votre navigation sur ce site ou en cliquant sur le bouton "J'accepte", vous consentez à ce que Vidal France et ses partenaire utilisent des cookies à des fins de mesure d'audience, de personnalisation des contenus, d'interaction avec les réseaux sociaux, ainsi que pour vous proposer des publicités adaptées à vos centres d’intérêts. It allows continued monitoring of the benefit/risk balance of the medicinal product. Augmentin® est un antibiotique de la famille des pénicillines.Il contient deux principes actifs: l'amoxicilline et l'acide clavulanique, ce qui lui permet d'être efficace contre bon nombre de bactéries.Ce médicament est délivré en pharmacie sur ordonnance sous différentes présentations pour adulte, enfants et nourrissons.

Augmentin IV for bolus injection should be administered within 20 min of reconstitution.Augmentin IV must be reconstituted as described above for injection. The sodium content of each vial or bottle is 62.9 mg (2.7 mmol).The potassium content of each vial or bottle is 39.3 mg (1.0 mmol).Vials containing a white to off-white sterile powder.Vials or bottles containing a white to off-white sterile powder.Augmentin is indicated for the treatment of the following infections in adults and children (see sections 4.2, 4.4 and 5.1):• Severe infections of the ear, nose and throat (such as mastoiditis, peritonsillar infections, epiglottitis, and sinusitis when accompanied by severe systemic signs and symptoms)• Acute exacerbations of chronic bronchitis (adequately diagnosed)• Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis• Bone and joint infections, in particular osteomyelitisProphylaxis against infections associated with major surgical procedures in adults, such as those involving the:Consideration should be given to official guidance on the appropriate use of antibacterial agents.Doses are expressed throughout in terms of amoxicillin/clavulanic acid content except when doses are stated in terms of an individual component.The dose of Augmentin that is selected to treat an individual infection should take into account:• The expected pathogens and their likely susceptibility to antibacterial agents (see section 4.4)• The age, weight and renal function of the patient as shown below. Augmentin susp Childn Skin & soft tissue infection, recurrent tonsillitis 20-40 mg/kg/day tid or 25-45 mg/kg/day bid. From a microbiological point of view, the reconstituted and diluted solution (1 reconstituted vial in a minimum volume of 50 ml of infusion fluid) should be used immediately. osteomyelitis) require longer periods of treatment.

Heat and dampness can destroy some medicines. This reaction requires Augmentin discontinuation and contraindicates any subsequent administration of amoxicillin.Amoxicillin/clavulanic acid should be used with caution in patients with evidence of hepatic impairment (see sections 4.2, 4.3 and 4.8).Hepatic events have been reported predominantly in males and elderly patients and may be associated with prolonged treatment. Mechanism of Action of Drugs. The two main mechanisms of resistance to amoxicillin/clavulanic acid are:• Inactivation by those bacterial beta-lactamases that are not themselves inhibited by clavulanic acid, including class B, C and D.• Alteration of PBPs, which reduce the affinity of the antibacterial agent for the target.Impermeability of bacteria or efflux pump mechanisms may cause or contribute to bacterial resistance, particularly in Gram-negative bacteria.