The drip will go through a pump. Patients with compromised renal function may show some measurable changes in pharmacokinetic parameters of CYTOXAN metabolism, but there is no consistent evidence indicating a need for CYTOXAN dosage modification in patients with renal function impairment.An oral dose of 2.5 to 3 mg/kg daily for a period of 60 to 90 days is recommended. Nearly all patients treated with cyclophosphamide experience some suppression of the bone marrow’s ability to produce these vital blood elements. As with many of cyclophosphamide’s side–effects, the risk of infertility appears to be related to the length of time a patient receives the drug (and probably the cumulative dose, as well). You will see a doctor or nurse before you have chemotherapy.
Often patients will receive one gram per day for up to three days.
The first round I tried taking more of the steroid but can't say that helped. We also include some less common side effects.
In males, the incidence of oligospermia and azoospermia increases if the duration of CYTOXAN treatment exceeds 60 days. CYTOXAN, constituted in water, is hypotonic and should not be injected directlyWe comply with the HONcode standard for trustworthy health information -
Intravenous steroids can cause patients to retain salt and fluid, leading to a gain of three to five pounds during a 3-5 day course of treatment. Share experiences, ask questions and talk to people who understand. This includes:Some people may need a drip to give them extra platelets.
Patients who feel sick should call their doctor immediately so that they can be prescribed antibiotics if needed. Oral CYTOXAN dosing is usually in the range of 1 to 5 mg/kg/day for both initial and maintenance dosing.
This is because the drugs could be passed to the baby through breast milk.If you need medical treatment for any reason other than cancer, always tell the doctors and nurses that you are having cancer treatment. This is called a Cyclophosphamide may irritate your bladder and cause discomfort when you pass urine (pee). After your treatment is over, most side effects start to improve.Some cancer treatments can cause severe side effects. Therefore, blood cell counts should be measured approximately 10 days after the administration of cyclophosphamide, and repeated as often as needed to insure that the counts do not go too low.
It is not uncommon for patients to have neutropenia (very low white blood count); because white blood cells play a key role in the bodyâs immune response, it is important to monitor for infection. 75mg), it is important not to break the tablets.
Cytoxan Images. Applies to cyclophosphamide: capsule, powder for solution, tablet. It was discovered that — in addition to its usefulness in cancer — cyclophosphamide also has a significant ability to suppress the immune system.
Many other regimens of intravenous and oral CYTOXAN have been reported. On the first day, you will have doxorubicin and cyclophosphamide.
What does Cytoxan look like? If the treatment is causing Other conditions can cause these symptoms, but it is important to get them checked by a doctor.This treatment can cause changes to the lungs. Tell your doctor if you have any bruising or bleeding that you cannot explain.
When used as the only oncolytic drug therapy, the initial course of CYTOXAN for patients with no hematologic deficiency usually consists of 40 to 50 mg/kg given intravenously in divided doses over a period of 2 to 5 days. Try different foods to find out what tastes best to you. This is due to Cytoxanâs suppression of both white and red blood cells. Cyclophosphamide, also called Cytoxan, is classified as a “cytotoxic agent”, because it has a toxic effect on many types of cells (“good” cells as well as “bad”). In this case the physician would administer a âpulse steroidâ which is a few days of a high dose of intravenous steroid in order to maintain the oral dose or even taper off the oral dose. It is important to take them exactly as your nurse or pharmacist explains. With those side–effects, the risk of their occurrence diminishes greatly after discontinuation of the drug.
This medication is not used for generalized lupus flares or for skin issues.The typical dosage is 500â1000 mg. If you need to take a dose requiring half a permanenttablet (e.g. In general, much lower doses of cyclophosphamide are used to treat vasculitis than are used to treat cancer.
Tell your nurse straight away if you have any stinging, pain, redness or swelling around the vein.If you get any of these symptoms after you get home, contact the doctor or nurse straight away on the contact telephone number they gave you.You may get pain at the place where the injection is given or along the vein. During treatment and for several months afterwards, you'll be more sensitive to the sun and your skin may burn more easily than usual.
In contrast, the risk of cancer associated with cyclophoshamide use may continue for many years, even after patients stop the medication. When cyclophosphamide is given orally (i.e., every day, rather than once a month), blood counts should be checked about 7 days after starting treatment and then not less frequently than once every 3 weeks. Tell your doctor if you develop: Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website. Cytoxan is initially administered at a low dose and slowly increased based on the cell counts during the nadir phase. Thus, careful monitoring of blood counts is essential during cyclophosphamide therapy.
Note: This document contains side effect information about cyclophosphamide. Some of the dosage forms listed on this page may not apply to the brand name Cytoxan.. For the Consumer.
Infusion time is about 1-2 hours. If you feel unwell or need advice, you can call them at any time of the day or night.
While on Rituxan, patients should not receive live vaccines.Patients may experience mild to severe infusion reactions such as chills, itching, high temperature, hives, difficulty breathing, and chest pain.