Just didn't want to get up this morning. All participants received 1000 mg of elemental calcium plus 400 to 1000 international units of vitamin D supplementation per day.The incidence of all-cause mortality was similar between treatment groups: 0.9% in the Reclast group and 0.7% in the active control group. I had the worst flue like aching for 5 days then my lefty arm became full of inflammation in the wrist, elbow and shoulder which caused extreme pain and I lost the ability to straighten my elbow. The doctor that prescribed it said he had never heard of this kind of reaction and the ER doctor was totally in the dark. Fluid Retention In The Legs, Feet, Arms Or Hands 11. However, there were no patients with adjudicated serious adverse events of atrial fibrillation in the Reclast treatment group.There were no patients who had treatment emergent serum calcium levels below 7.5 mg/dL.There were 4 patients (2.6%) on Reclast vs. 2 patients (1.4%) on active control with local site reactions.In this trial there were no cases of osteonecrosis of the jaw [see The safety of Reclast in men and women in the treatment and prevention of glucocorticoid-induced osteoporosis was assessed in a randomized, multicenter, double-blind, active controlled, stratified study of 833 men and women aged 18 to 85 years treated with greater than or equal to 7.5 mg/day oral prednisone (or equivalent). The percentage of subjects who withdrew from the study due to adverse events was 2.2% in the Reclast group vs. 1.4% in the active control group. You might want to check that out too. No symptomatic cases of hypocalcemia were observed. The percentage of patients who withdrew from the study due to adverse events was 1.7% and 1.2% for the Reclast and risedronate groups, respectively.Adverse reactions occurring in at least 2% of the Paget’s patients receiving Reclast (single 5 mg intravenous infusion) or risedronate (30 mg oral daily dose for 2 months) over a 6-month study period are listed by system organ class in Table 4.In clinical trials in Paget’s disease there were no cases of renal deterioration following a single 5 mg 15-minute infusion [see The signs and symptoms of acute phase reaction (influenza-like illness, pyrexia, myalgia, arthralgia, and bone pain) were reported in 25% of patients in the Reclast-treated group compared to 8% in the risedronate-treated group. Then she started having side effects. Thanks, @JustinMcClanahan for adding me. In the clinical trial for postmenopausal osteoporosis, patients with baseline creatinine clearance less than 30 mL/min (based on actual body weight), urine dipstick greater than or equal to 2+ protein or increase in serum creatinine of greater than 0.5 mg/dL during the screening visits were excluded. Thanks, @JustinMcClanahan for adding me. Other musculoskeletal events included back pain (Reclast 4.3%, active control 6.2%), bone pain (Reclast 3.1%, active control 2.2%), and pain in the extremity (Reclast 3.1%, active control 1.2%).
Three weeks ago I had my first Reclast infusion. Has anyone had a good experience with this drug?

as the weeks have gone on - the side effects have continued to get worse and worse. I think I’m ready to go ahead and get the infusion, but there is so much negative information out there that I found myself scared to move forward, especially after developing gastritis while using the Fosamax. I hope you keep coming back to the community, there are many great members on here that are willing to not just offer advice or experiences, but willing to listen. You may eat before your treatment with Reclast. Transient rise in serum creatinine can be correctable with intravenous fluids.Allergic reactions with intravenous zoledronic acid including anaphylactic reaction/shock, urticaria, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, and bronchoconstriction have been reported.Cases of osteonecrosis of other bones (including femur, hip, knee, ankle, wrist and humerus) have been reported; causality has not been determined in the population treated with Reclast.Cases of the following events have been reported: conjunctivitis, iritis, iridocyclitis, uveitis, episcleritis, scleritis and orbital inflammation/edema.Hypotension in patients with underlying risk factors has been reported.© Reclast Patient Information is supplied by Cerner Multum, Inc. and Reclast Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment.
But I haven’t seen anyone say how long that problem lasted and what they did to get rid of the swelling.