You may need to try a different medication. Threej. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. All rights reserved. “In all cases, the frequency is hard to gauge and is based on an interplay between unique genes and unique life experiences and stressors,” he says. Get it daily.Recently, the actress and comedian Sarah Silverman shared a post on  claiming that she’d “officially built a tolerance to Zoloft.” Comments from followers came pouring in—some congratulating her on boldly speaking about something private, and others sharing their own similar experiences with antidepressants. Zoloft worked for me right away but became less effective after about 6 weeks. Zoloft not working? Elana Lyn Gross ・ ... From a chemical perspective, it’s not clear why some people become tolerant to … How long is a dose increase suppose to take to come in effect. It does go away. If it’s been more than a few weeks, then yeah, it’s probably not working. For me Zoloft did not work personally...just wanted to sleep all the time..I have heard it has work for some people ok..but not for me. You may eventually have tried several different medications before you find the right one (or combination thereof). Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.

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I hope this helps some of y’all, and if anyone has anything to add to it, please let me know!!! Antidepressant tolerance is usually marked by specific symptoms, the most common being apathy, fatigue, and lack of motivation.

My plan is to go to my doctor and switch to a new medication. It’s hard to get in the mood sometimes. Asked 21 Sep 2014 by Omarbadawi Updated 11 April 2015 Topics zoloft, depression, major depressive disorder. It’s called “antidepressant tolerance” in common parlance, but the official name isSo how does tolerance happen, and how do you deal if it’s happening to you? All rights reserved. It never occurred to me that the Zoloft just wasn't working anymore until I discovered on several forums that many depression sufferers also had an experience with Zoloft losing it's effectiveness over time.


Psychological counseling (psychotherapy) also may help.Because there are so many reasons depression treatment can stop working, you may need to see a medical doctor who specializes in diagnosing and treating mental illness (psychiatrist) to figure out the best course of action.Mayo Clinic does not endorse companies or products. Reply (0) Report. If you start to notice symptoms of antidepressant tolerance or anything else that’s worrisome, Dr. Schlozman says to contact your doctor right away. How long have you been taking it? Your doctor may recommend that you change the dose of your current antidepressant, change to another antidepressant or add another antidepressant or other type of medication to your current treatment. Mayo Clinic does not endorse any of the third party products and services advertised.A single copy of these materials may be reprinted for noncommercial personal use only. Schedule a medication … “The treatment of depression is always some combination of medicines as well as life changes that decrease stress,” says Dr. Schlozman. The telltale sign of antidepressant tolerance is this: You felt better after having taken the drugs for four or more months, but then your symptoms returned, according to Dr. Schlozman. There also can be other reasons an antidepressant is no longer working for you, such as: Worsening depression. I've thought before these aren't working I'm not taking them anymore and by the 3rd day I'm a mess so I guess they are doing something.