Famotidine was thought to possibly bind a papain-like protease that is … We explore several plausible avenues of activity including antiviral and host-mediated actions. The number of participants with "adverse effects" determined by the existence of the pharmacological side effects of the particular drug (Famotidine) during treatment.The adverse effect will define as the symptoms expressed by the participants following the starting of the treatment other than the disease symptoms, those are within the proven/enlisted pharmacological side effects of the particular drug therapy.

The study will include COVID-19 participants to confirm by RT PCR or an HRCT chest. COVID-19, viruses, histamine, famotidine, mast cells Lincoln Laboratory, Hence SARS-CoV-2 is a novel virus; there is no specific medication against it.

Future work will investigate potential mechanisms of action and clinical relevance of famotidine. Seriously ill patients who require ventilation will not be included in this study. This will be defined as OPD patients require hospitalization, Hospitalized patients require High Dependency Unit (HDU), and an HDU patient requiring Ventilator or Intensive care support.Keywords provided by Abu Taiub Mohammed Mohiuddin Chowdhury, First Affiliated Hospital Xi'an Jiaotong University: Like other countries of the world, Besides antiviral drugs, immunosuppressive agents, and symptomatic therapy like H2 receptor blocker FAMOTIDINE … Clinical data suggest that famotidine may mitigate COVID-19 disease, but both mechanism of action and rationale for dose selection remain obscure. Many pharmacologic therapies are being used or considered for treatment. Journal Article Major symptoms, fever, cough, respiratory distress, chest tightness, sore throat, and myalgia will be rerecorded daily. Famotidine inhibits both basal and nocturnal gastric acid secretion, as well as acid secretion stimulated by food, caffeine, insulin, and pentagastrin.

Currently, there are no pre- or post-exposure prophylactic COVID-19 medical countermeasures.

This study is aimed to investigate the effect of Famotidine in the symptomatic recovery of the different degrees of COVID-19 patients.

COVID-19 is an emerging, rapidly evolving situation.

Hanscom Air Force Base has declared Force Protection Condition Bravo.For questions or additional details about this or other Lincoln Laboratory publications, This will be done by the investigators in the case of the hospitalized patients and the patient itself by a daily self assessment cart in the case of OPD patients.The number of participants with "Clinical status (Stable or Deteriorate clinical state)" determined by the chart or the judgment of the investigators. Ten people who were home sick with Covid-19 may have found relief with a common over-the-counter heartburn remedy, according to a study published Thursday. Following oral administration, the … © 2020

You have reached the maximum number of saved studies (100).Please remove one or more studies before adding more.Abu Taiub Mohammed Mohiuddin Chowdhury, First Affiliated Hospital Xi'an Jiaotong UniversityThis study is aimed to investigate the effect of Famotidine in the symptomatic recovery of the different degrees of COVID-19 patients.

SARS-CoV-2 infection is required for COVID-19, but many signs and symptoms of COVID-19 differ from common acute viral diseases. COVID-19 is a pandemic with a rapidly increasing incidence of infections and deaths. COVID19 is a worldwide pandemic.

The mechanism of action for famotidine is not clear at this time. Patients who took a common heartburn medicine while hospitalized for Covid-19 were more than twice as likely to survive the infection, according to a paper posted Friday on a pre-publication website. May 23, 2020 Clinical data suggest that famotidine may mitigate COVID-19 disease, but both mechanism of action and rationale for dose selection … Hence SARS-CoV-2 is a novel virus; there is no specific medication against it. Detail history of each participant with comorbidity will be taken and will be examined carefully. Currently, there are no pre- or post-exposure prophylactic COVID-19 medical countermeasures. SARS-CoV-2 infection is required for COVID-19, but many signs and symptoms of COVID-19 differ from common acute viral diseases.